Amino Acid
Glycine (for Relaxation)
Also known as: Gly, Aminoacetic acid
Simplest amino acid with profound calming and sleep effects. Lowers body temperature.
Last reviewed June 2026 · Evidence graded from peer-reviewed research, not editorial opinion. Educational only — not medical advice.
Every Glycine (for Relaxation) product we have scored
| # | Product | Score | Per serving |
|---|---|---|---|
| 1 | Nutricost Glycine Powder | 92 A | $0.17 |
| 2 | Thorne Glycine | 92 A | $0.25 |
| 3 | Pure Encapsulations Glycine | 92 A | $0.58 |
| 4 | Life Extension Glycine | 92 A | $0.13 |
| 5 | NutraBio Glycine Powder | 92 A | $0.13 |
| 6 | Pure Encapsulations NAC + Glycine powder | 88 A | $1.27 |
| 7 | Pure Encapsulations Pure Tranquility Liquid | 87 A | $1.76 |
| 8 | Life Extension Optimized Carnitine | 87 A | $0.78 |
| 9 | Thorne MediClear-SGS™ - Vanilla | 86 A- | $2.10 |
| 10 | Vital Nutrients Glycine Powder | 85 A- | $0.60 |
| 11 | NOW Foods Double Strength 5-HTP | 84 A- | $0.37 |
| 12 | Swanson GABAplex with L-Tyrosine & L-Theanine | 84 A- | $0.28 |
Scored on dose accuracy, form, label transparency and third-party testing. Per-serving cost is list price divided by servings per container. No brand pays to be listed or ranked.
Common questions
How much Glycine (for Relaxation) should I take?
The typical range is 3g before bed. Safe nightly
When should I take Glycine (for Relaxation)?
30-60 min before bed. Either.
Which form of Glycine (for Relaxation) is best?
Powder — Sweet taste, easy to use. Other forms in the catalog: Capsule.
Is Glycine (for Relaxation) safe?
Commonly reported: Well tolerated, Sweet taste. Serious warnings: None. No concerns
Which Glycine (for Relaxation) supplement scores highest?
Nutricost Glycine Powder, at 92/100. Scored on dose accuracy, form, label transparency and third-party testing — no brand pays to be listed or ranked.
Primary uses
- Sleep quality
- Relaxation
- Cognitive function
How it works
- Lowers core body temperature
- Inhibitory neurotransmitter
- Collagen precursor
Dosage
- Typical range
- 3g before bed
- Timing
- 30-60 min before bed
- With food
- Either
- Duration
- Safe nightly
- Special populations
- Sleep quality, temperature regulation
Forms
- Powder
- Capsule
Safety
Common side effects
- Well tolerated
- Sweet taste
Contraindications
- None known
Products containing Glycine (for Relaxation)
Top-scoring supplements in our catalog that list Glycine (for Relaxation) on the label. Each product is graded on Formulate's ingredient-level rubric — dose accuracy, form, transparency, and third-party testing.
Evidence notes
Good evidence for sleep improvement
Grade B: Some human trials support key claims; further confirmation needed.
Related in Amino Acid
Check a full stack
Formulate's free interaction checker lets you paste in any combination of supplements and medications at once — every pairing flags severity, timing, and cited evidence.
Open the checkerWhere does Glycine (for Relaxation) fit in your stack?
Answer two questions and get a stack graded on research — every ingredient scored on the evidence behind it, not the marketing.
Build my stack2 questions · free · no account needed to start
Also on iPhone — get the free app
Evidence-based supplement guides, no spam
We send a short digest when new guides drop — nothing else. No affiliate pushes, no sponsored content, unsubscribe anytime.
Medical disclaimer. This page is educational and does not replace advice from a qualified healthcare provider. Individual needs and risks vary — consult a professional before starting, stopping, or combining supplements, especially if you are pregnant or nursing, taking medication, or managing a health condition.