Amino Acid

5-HTP

Also known as: 5-HTP (5-Hydroxytryptophan), 5-Hydroxytryptophan, Griffonia extract, Oxitriptan

Evidence

Direct serotonin precursor, one step closer than tryptophan. More potent for mood and appetite but requires more caution.

Primary uses

Mood support
Appetite control
Sleep
Fibromyalgia

How it works

Directly converts to serotonin
Crosses blood-brain barrier
Bypasses rate-limiting step

Dosage

Typical range: 50-200 mg daily
Timing: Evening for sleep; divided for mood
With food: With small carb
Duration: Cycling recommended
Special populations: Depression (with supervision), sleep

Forms

Capsules

Safety

Common side effects

Nausea
GI upset
Vivid dreams

Contraindications

SSRIs, MAOIs
Carcinoid tumors

Known interactions

Evidence notes

Direct serotonin precursor

Grade B: Some human trials support key claims; further confirmation needed.

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Medical disclaimer. This page is educational and does not replace advice from a qualified healthcare provider.