Tyrosine and 5-HTP compete for brain uptake
Both amino acids use the same transporter to cross the blood-brain barrier. Taking together may reduce effectiveness of both.
Take at different times of day for best effect.
Separate by 4+ hours; tyrosine in morning, 5-HTP in evening
Tyrosine and 5-HTP compete for brain uptake. Take at different times of day for best effect.
Separate by 4+ hours; tyrosine in morning, 5-HTP in evening
This interaction is rated “Warning” by Formulate. Both amino acids use the same transporter to cross the blood-brain barrier. Taking together may reduce effectiveness of both.
Other interactions to know
Risk of serotonin syndrome
Tyrosine can cause hypertensive crisis with MAOIs
Both increase serotonin - risk of excess
BCAAs may reduce tyrosine brain uptake
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Medical disclaimer. This page is for educational purposes only and does not replace advice from a qualified healthcare provider.
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