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Amino Acid

L-Glutamine (Gut/Detox)

Also known as: L-glutamine, Glutamine

A
Evidence

Conditionally essential amino acid that fuels enterocytes, supports gut barrier, and aids detox pathways.

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Daily target & upper limit

5 g / day

L-Glutamine (Gut/Detox) has an established daily reference intake. See best forms, label synonyms, upper-limit warnings, and top-scoring supplements:

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Primary uses

  • Gut barrier repair
  • Enterocyte fuel
  • Detox support
  • Immune function

How it works

  • Primary fuel for intestinal cells
  • Supports tight junction integrity
  • Precursor for glutathione
  • Supports immune cells

Dosage

Typical range
5-20g daily for gut healing, 2-5g for maintenance
Timing
Away from meals or divided throughout day
With food
Either way, often away from meals
Duration
Short-term high dose for healing, lower for maintenance
Special populations
Leaky gut, IBD, athletes, post-surgery

Forms

  • Powder
  • Capsules

Safety

Common side effects

  • Rare at typical doses

Contraindications

  • Hepatic encephalopathy
  • Severe liver disease

Products containing L-Glutamine (Gut/Detox)

Top-scoring supplements in our catalog that list L-Glutamine (Gut/Detox) on the label. Each product is graded on Formulate's ingredient-level rubric — dose accuracy, form, transparency, and third-party testing.

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Evidence notes

Strong evidence for gut barrier and critical illness

Grade A: Multiple well-designed human trials support the main claims.

Cited research for L-Glutamine (Gut/Detox)

Clinical studies referenced across Formulate guides that mention l-glutamine (gut/detox). Each links to the full study page with PubMed source + the guides that cite it.

Related in Amino Acid

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Medical disclaimer. This page is educational and does not replace advice from a qualified healthcare provider.