Amino Acid
L-Glutamine (Gut Repair)
Also known as: Glutamine, L-glutamine
A
Evidence
Primary fuel for intestinal cells, essential for gut barrier repair and reducing intestinal permeability.
Primary uses
- Gut barrier repair
- Leaky gut
- IBD support
- Enterocyte fuel
How it works
- Primary fuel for enterocytes
- Supports tight junction integrity
- Reduces intestinal permeability
- Aids mucosal healing
Dosage
- Typical range
- 5-20g daily for gut healing, 2-5g maintenance
- Timing
- Away from protein meals or divided throughout day
- With food
- Either way
- Duration
- High dose 2-3 months for healing, then maintenance
- Special populations
- Leaky gut, IBD, post-antibiotic, athletes
Forms
- Powder
- Capsules
Safety
Common side effects
- Rare at normal doses
Contraindications
- Hepatic encephalopathy
- Severe liver disease
Evidence notes
Strong evidence for gut barrier support
Grade A: Multiple well-designed human trials support the main claims.
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