Amino Acid
D-Aspartic Acid (DAA)
Also known as: DAA, D-AA, D-Aspartate
Amino acid involved in testosterone synthesis, with mixed research results.
Last reviewed June 2026 · Evidence graded from peer-reviewed research, not editorial opinion. Educational only — not medical advice.
Primary uses
- Testosterone synthesis
- LH stimulation
- Male fertility
How it works
- Stimulates LH release
- Involved in testosterone synthesis
- May help subfertile men
- Effects in healthy men unclear
Dosage
- Typical range
- 2-3g daily
- Timing
- Morning
- With food
- Either way
- Duration
- Cycle 2-3 weeks on, 1-2 weeks off
- Special populations
- Men with suboptimal fertility/testosterone
Forms
- Powder
- Capsules
Safety
Common side effects
- Irritability
- Headache
- Acne (some)
Contraindications
- None significant
Evidence notes
Mixed results - may help subfertile men more than healthy men
Grade C: Mostly observational or small trials; mechanism is plausible but unproven at scale.
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Medical disclaimer. This page is educational and does not replace advice from a qualified healthcare provider. Individual needs and risks vary — consult a professional before starting, stopping, or combining supplements, especially if you are pregnant or nursing, taking medication, or managing a health condition.