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Digestive

Bromelain

Also known as: Pineapple enzyme, Bromelain (Wound Healing), Proteolytic enzyme

B
Evidence

Pineapple-derived protease enzyme supporting protein digestion and having anti-inflammatory properties.

Last reviewed June 2026 · Evidence graded from peer-reviewed research, not editorial opinion. Educational only — not medical advice.

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Primary uses

  • Protein digestion
  • Inflammation
  • Sinus support
  • Injury recovery
  • Swelling reduction
  • Bruising
  • Surgery recovery
  • Anti-inflammatory
  • Sinusitis
  • Wound healing

How it works

  • Proteolytic enzyme activity
  • Anti-inflammatory effects systemic
  • Fibrinolytic properties

Dosage

Typical range
500-2000 GDU daily
Timing
Between meals for inflammation; with meals for digestion
With food
Depends on goal
Duration
Safe long-term
Special populations
Surgery recovery, sinusitis

Forms

  • Capsules
  • Tablets
  • Enteric-coated

Safety

Common side effects

  • GI upset
  • Diarrhea

Contraindications

  • Before surgery
  • Bleeding disorders

Products containing Bromelain

Top-scoring supplements in our catalog that list Bromelain on the label. Each product is graded on Formulate's ingredient-level rubric — dose accuracy, form, transparency, and third-party testing.

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Evidence notes

Digestive and anti-inflammatory uses

Grade B: Some human trials support key claims; further confirmation needed.

Related in Digestive

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Medical disclaimer. This page is educational and does not replace advice from a qualified healthcare provider. Individual needs and risks vary — consult a professional before starting, stopping, or combining supplements, especially if you are pregnant or nursing, taking medication, or managing a health condition.