Skip to main content

zinc and copper

Zinc depletes copper over time

What's happening

Long-term zinc supplementation (>40mg/day) can induce copper deficiency by competing for absorption. This can lead to anemia and neurological issues.

Recommendation

If taking zinc long-term, supplement with copper (ratio of ~15:1 zinc:copper) or take copper separately.

Timing

Take zinc and copper at different times of day (4+ hours apart)

Sources

  • — NIH Office of Dietary Supplements
  • — Journal of Trace Elements

Frequently Asked Questions

Can I take zinc and copper together?

Zinc depletes copper over time. If taking zinc long-term, supplement with copper (ratio of ~15:1 zinc:copper) or take copper separately.

How should I time zinc and copper?

Take zinc and copper at different times of day (4+ hours apart)

Is this interaction dangerous?

This interaction is rated “Warning” by Formulate. Long-term zinc supplementation (>40mg/day) can induce copper deficiency by competing for absorption. This can lead to anemia and neurological issues.

Want to check your whole stack?

The free checker lets you add any combination of supplements and medications at once. Formulate's desktop app goes further — every stack change surfaces interaction alerts automatically.

Open the checkerGet the desktop app

Medical disclaimer. This page is for educational purposes only and does not replace advice from a qualified healthcare provider.