Herbal Extract
Vitex (Agnus Castus) Extract
Also known as: Chasteberry, Chaste Tree, Vitex agnus-castus, Monk's Pepper
Vitex is a traditional herbal extract used to support hormonal balance, particularly for menstrual cycle regulation and premenstrual symptoms in women. Evidence for efficacy is moderate, with some clinical studies supporting symptom relief but limited mechanistic understanding.
Primary uses
- Premenstrual syndrome (PMS) support
- Menstrual cycle regulation
- Hormonal balance
How it works
- Dopamine agonism (may suppress prolactin)
- Modulation of luteal phase progesterone
Dosage
- Typical range
- 400-500 mg daily standardized extract
- Timing
- Morning, consistently daily
- With food
- Can be taken with or without food
- Duration
- May require 2-3 months of consistent use to observe effects on menstrual cycle
- Special populations
- Not recommended during pregnancy; use with caution while breastfeeding
Forms
- Extract· 70/100
- Capsule· 70/100
- Tablet· 70/100
Safety
Common side effects
- Headache
- Gastrointestinal upset
- Breast tenderness
- Mild rash
Contraindications
- Pregnancy
- Hormone-sensitive cancers (theoretical risk)
- Concurrent dopamine antagonist use
Evidence notes
Multiple RCTs demonstrate efficacy for PMS symptoms; however, mechanism of action remains incompletely understood and some studies are small or have methodological limitations.
Grade B: Some human trials support key claims; further confirmation needed.
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