Adaptogen
Sensoril® Ashwagandha (Withania somnifera) Extract
Also known as: Withania somnifera, Indian ginseng, Winter cherry, Ashwagandha extract
Sensoril® is a standardized ashwagandha extract derived from root and leaf that contains bioactive withanolides, compounds studied for stress reduction and cognitive support. Multiple randomized controlled trials support its efficacy for reducing cortisol and anxiety symptoms.
Primary uses
- Stress and anxiety reduction
- Cortisol modulation
- Sleep quality improvement
- Cognitive function support
- Mood enhancement
How it works
- Withanolide-mediated HPA axis regulation
- GABA receptor modulation
- Anti-inflammatory signaling
- Antioxidant activity
Dosage
- Typical range
- 225-600 mg daily (standardized to withanolides)
- Timing
- With meals; often divided into 2-3 doses
- With food
- Recommended; improves absorption and tolerability
- Duration
- Consistent use for 4-8 weeks typically needed for optimal effects; benefits may continue with long-term use
- Special populations
- Pregnant/nursing women should consult healthcare provider; may interact with sedating medications
Forms
- Capsule· 70/100
- Standardized extract powder· 70/100
Safety
Common side effects
- Mild gastrointestinal upset
- Drowsiness (at higher doses)
- Headache (rare)
Contraindications
- Pregnancy and lactation (traditionally used in some cultures but consult provider)
- Thyroid disorders (may have mild thyroid effects)
- Immunosuppressed individuals (immune-stimulating properties)
Evidence notes
Strong evidence from multiple RCTs demonstrating efficacy for stress, anxiety, and cortisol reduction. Sensoril® specifically has published clinical trials. Grade B rather than A due to variability in study quality and effect sizes, though human evidence is substantial.
Grade B: Some human trials support key claims; further confirmation needed.
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