Adaptogen
Reishi (Ganoderma lucidum s.l.)
Also known as: Ganoderma lucidum, lingzhi, reishi extract, reishi mycelium
Reishi is a polypore mushroom used for centuries in Traditional Chinese Medicine as an adaptogenic tonic for stress, sleep, and immune support. Moderate clinical evidence supports anxiolytic and sleep-promoting effects.
Last reviewed June 2026 · Evidence graded from peer-reviewed research, not editorial opinion. Educational only — not medical advice.
Every Reishi (Ganoderma lucidum s.l.) product we have scored
| # | Product | Score | Per serving |
|---|---|---|---|
| 1 | Complement Restore | 86 A- | $1.90 |
| 2 | Double Wood Reishi Mushroom Extract Supplement | 83 A- | $0.13 |
| 3 | Terra Origin Healthy Mushroom Capsules | 83 A- | $1.00 |
| 4 | New Chapter Fermented Vitamin D3 | 81 A- | $0.42 |
| 5 | Thorne Daily Greens Plus | 79 B+ | $0.83 |
| 6 | Pure Encapsulations PureResponse Multivitamin | 78 B+ | $1.17 |
| 7 | Pure Encapsulations M/R/S Mushroom Formula | 76 B+ | $0.62 |
| 8 | NOW Foods Adrenal Stress Support | 73 B+ | $0.22 |
| 9 | MegaFood Adrenal Strength | 73 B+ | $1.33 |
| 10 | Micro Ingredients Organic Mega 10 mushroom Powder | 66 B- | $0.14 |
| 11 | Natural Factors Super Mushroom | 64 B- | $1.13 |
| 12 | Gaia Herbs Reishi Mushroom | 59 C+ | $0.74 |
Scored on dose accuracy, form, label transparency and third-party testing. Per-serving cost is list price divided by servings per container. No brand pays to be listed or ranked.
Common questions
How much Reishi (Ganoderma lucidum s.l.) should I take?
The typical range is 1,000–2,500 mg daily (dried mycelium biomass); extract forms often 300–900 mg. Safe for long-term chronic use; benefits may emerge over 4–12 weeks
When should I take Reishi (Ganoderma lucidum s.l.)?
evening for sleep support; morning/throughout day for general adaptogenic effects. may be taken with or without food.
Which form of Reishi (Ganoderma lucidum s.l.) is best?
mycelium biomass on rice. Other forms in the catalog: extract, powder, standardized extract.
Is Reishi (Ganoderma lucidum s.l.) safe?
Commonly reported: rare: mild GI upset, dizziness, occasional dry mouth.
Which Reishi (Ganoderma lucidum s.l.) supplement scores highest?
Complement Restore, at 86/100. Scored on dose accuracy, form, label transparency and third-party testing — no brand pays to be listed or ranked.
Primary uses
- stress reduction
- sleep support
- immune support
- relaxation
How it works
- polysaccharide and triterpene-mediated adaptogenic effects
- GABAergic pathway modulation
- immunomodulation
- stress hormone regulation
Dosage
- Typical range
- 1,000–2,500 mg daily (dried mycelium biomass); extract forms often 300–900 mg
- Timing
- evening for sleep support; morning/throughout day for general adaptogenic effects
- With food
- may be taken with or without food
- Duration
- Safe for long-term chronic use; benefits may emerge over 4–12 weeks
- Special populations
- Pregnant/nursing women should consult healthcare provider; immunosuppressed patients should check with provider
Forms
- mycelium biomass on rice· 70/100
- extract· 70/100
- powder· 70/100
Safety
Common side effects
- rare: mild GI upset, dizziness
- occasional dry mouth
Contraindications
- immunosuppressant therapy (theoretical concern)
- bleeding disorders (high-dose triterpenes theoretically anticoagulant)
Products containing Reishi (Ganoderma lucidum s.l.)
Top-scoring supplements in our catalog that list Reishi (Ganoderma lucidum s.l.) on the label. Each product is graded on Formulate's ingredient-level rubric — dose accuracy, form, transparency, and third-party testing.
Evidence notes
Multiple human trials show benefits for sleep, anxiety, and immune markers. Evidence is moderate quality; some studies are small or lack rigorous controls, but consistent benefit signals exist.
Grade B: Some human trials support key claims; further confirmation needed.
Related in Adaptogen
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Medical disclaimer. This page is educational and does not replace advice from a qualified healthcare provider. Individual needs and risks vary — consult a professional before starting, stopping, or combining supplements, especially if you are pregnant or nursing, taking medication, or managing a health condition.