Adaptogen
Ganoderma lucidum Extract (Reishi Fruiting Body)
Also known as: Reishi, Lingzhi, Red Reishi, Ganoderma lucidum fruiting body
Ganoderma lucidum (reishi) is a medicinal mushroom traditionally used in Asian medicine with modern research suggesting potential benefits for stress resilience, sleep quality, and immune support. The 8:1 extract ratio indicates concentration of active compounds including polysaccharides and triterpenes.
Last reviewed June 2026 · Evidence graded from peer-reviewed research, not editorial opinion. Educational only — not medical advice.
Every Ganoderma lucidum Extract (Reishi Fruiting Body) product we have scored
| # | Product | Score | Per serving |
|---|---|---|---|
| 1 | Complement Restore | 86 A- | $1.90 |
| 2 | Double Wood Reishi Mushroom Extract Supplement | 83 A- | $0.13 |
| 3 | Terra Origin Healthy Mushroom Capsules | 83 A- | $1.00 |
| 4 | New Chapter Fermented Vitamin D3 | 81 A- | $0.42 |
| 5 | Thorne Daily Greens Plus | 79 B+ | $0.83 |
| 6 | Pure Encapsulations PureResponse Multivitamin | 78 B+ | $1.17 |
| 7 | Pure Encapsulations M/R/S Mushroom Formula | 76 B+ | $0.62 |
| 8 | NOW Foods Adrenal Stress Support | 73 B+ | $0.22 |
| 9 | MegaFood Adrenal Strength | 73 B+ | $1.33 |
| 10 | Micro Ingredients Organic Mega 10 mushroom Powder | 66 B- | $0.14 |
| 11 | Natural Factors Super Mushroom | 64 B- | $1.13 |
| 12 | Gaia Herbs Reishi Mushroom | 59 C+ | $0.74 |
Scored on dose accuracy, form, label transparency and third-party testing. Per-serving cost is list price divided by servings per container. No brand pays to be listed or ranked.
Common questions
How much Ganoderma lucidum Extract (Reishi Fruiting Body) should I take?
The typical range is 500–2,000 mg daily in divided doses. Typically requires 2–8 weeks of consistent use for noticeable effects; benefits often increase with longer use
When should I take Ganoderma lucidum Extract (Reishi Fruiting Body)?
Morning and evening; evening dose may support sleep. May be taken with or without food; water extraction has better bioavailability.
Which form of Ganoderma lucidum Extract (Reishi Fruiting Body) is best?
Fruiting body extract (water extraction standard). Other forms in the catalog: Capsules, Powder, Tincture, Powder extract (8:1 concentration), Whole fruiting body dried.
Is Ganoderma lucidum Extract (Reishi Fruiting Body) safe?
Commonly reported: Mild gastrointestinal upset, Dry mouth, Dizziness (rare), Mild insomnia if taken in excess.
Which Ganoderma lucidum Extract (Reishi Fruiting Body) supplement scores highest?
Complement Restore, at 86/100. Scored on dose accuracy, form, label transparency and third-party testing — no brand pays to be listed or ranked.
Primary uses
- Stress and anxiety reduction
- Sleep quality improvement
- Immune system support
- General wellness and adaptogenic support
- Stress and anxiety support
- General wellness and adaptogenic effects
How it works
- Bioactive polysaccharides (β-glucans) may modulate immune function via pattern recognition receptors
- Triterpenes and peptidoglycans may influence HPA axis and stress response
- Potential GABAergic activity supporting relaxation
- Antioxidant and anti-inflammatory effects
Dosage
- Typical range
- 500–2,000 mg daily in divided doses
- Timing
- Morning and evening; evening dose may support sleep
- With food
- May be taken with or without food; water extraction has better bioavailability
- Duration
- Typically requires 2–8 weeks of consistent use for noticeable effects; benefits often increase with longer use
- Special populations
- Safety in pregnancy and lactation not well established; use caution in immunocompromised individuals taking immunosuppressants
Forms
- Fruiting body extract (water extraction standard)· 70/100
- Capsules· 70/100
- Powder· 70/100
- Tincture· 70/100
- Whole fruiting body dried· 70/100
Safety
Common side effects
- Mild gastrointestinal upset
- Dry mouth
- Dizziness (rare)
- Mild insomnia if taken in excess
Contraindications
- Concurrent immunosuppressant therapy (potential interaction)
- Bleeding disorders or anticoagulant use (theoretical risk, case reports limited)
- Pregnancy and lactation (insufficient safety data)
Products containing Ganoderma lucidum Extract (Reishi Fruiting Body)
Top-scoring supplements in our catalog that list Ganoderma lucidum Extract (Reishi Fruiting Body) on the label. Each product is graded on Formulate's ingredient-level rubric — dose accuracy, form, transparency, and third-party testing.
Evidence notes
Reishi has moderate human clinical evidence for stress/anxiety and sleep support, with some well-designed RCTs showing benefit. However, studies are often small-scale or from Asian institutions with variable methodology. Fruiting body extracts are generally considered superior to mycelium products.
Grade B: Some human trials support key claims; further confirmation needed.
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Medical disclaimer. This page is educational and does not replace advice from a qualified healthcare provider. Individual needs and risks vary — consult a professional before starting, stopping, or combining supplements, especially if you are pregnant or nursing, taking medication, or managing a health condition.