Adaptogen
Reishi
Also known as: Lingzhi, Ganoderma lucidum, Reishi (Ganoderma lucidum), Spirit mushroom
The 'mushroom of immortality' - adaptogenic fungus that modulates immune function, reduces stress, and supports longevity.
Last reviewed June 2026 · Evidence graded from peer-reviewed research, not editorial opinion. Educational only — not medical advice.
Every Reishi product we have scored
| # | Product | Score | Per serving |
|---|---|---|---|
| 1 | Complement Restore | 86 A- | $1.90 |
| 2 | Double Wood Reishi Mushroom Extract Supplement | 83 A- | $0.13 |
| 3 | Terra Origin Healthy Mushroom Capsules | 83 A- | $1.00 |
| 4 | New Chapter Fermented Vitamin D3 | 81 A- | $0.42 |
| 5 | Thorne Daily Greens Plus | 79 B+ | $0.83 |
| 6 | Pure Encapsulations PureResponse Multivitamin | 78 B+ | $1.17 |
| 7 | Pure Encapsulations M/R/S Mushroom Formula | 76 B+ | $0.62 |
| 8 | NOW Foods Adrenal Stress Support | 73 B+ | $0.22 |
| 9 | MegaFood Adrenal Strength | 73 B+ | $1.33 |
| 10 | Micro Ingredients Organic Mega 10 mushroom Powder | 66 B- | $0.14 |
| 11 | Natural Factors Super Mushroom | 64 B- | $1.13 |
| 12 | Gaia Herbs Reishi Mushroom | 59 C+ | $0.74 |
Scored on dose accuracy, form, label transparency and third-party testing. Per-serving cost is list price divided by servings per container. No brand pays to be listed or ranked.
Common questions
How much Reishi should I take?
The typical range is 1000-3000mg or 300-500mg extract. Safe long-term
When should I take Reishi?
Evening (calming) or morning. Either.
Which form of Reishi is best?
Capsule — Extract. Other forms in the catalog: Powder, Fruiting body extract, Dual extract (water + alcohol), Spore oil.
Is Reishi safe?
Commonly reported: GI upset, Dizziness, Dry mouth. Serious warnings: May affect blood clotting. Rare liver issues
Which Reishi supplement scores highest?
Complement Restore, at 86/100. Scored on dose accuracy, form, label transparency and third-party testing — no brand pays to be listed or ranked.
Primary uses
- Immune modulation
- Sleep quality
- Stress adaptation
- Longevity
- Sleep support
What systematic reviews concluded
Outcomes that systematic reviews of Reishi reached a verdict on: 1 with a benefit, 1 unclear. Each is quoted from a review and linked to it on PubMed. How these were read.
Reviews found a benefit (1)
“Supplementation with beta-(1 → 3,1 → 6)-d-glucans is well-tolerated, and health-promoting properties are manifested primarily through the potentiation of the immune system.” PMID 33876798
Not enough to say: depressive symptoms.
How it works
- Beta-glucans for immune modulation
- Triterpenes for calming
- Adaptogenic
Dosage
- Typical range
- 1000-3000mg or 300-500mg extract
- Timing
- Evening (calming) or morning
- With food
- Either
- Duration
- Safe long-term
- Special populations
- Immune, sleep, stress
Forms
- Capsule
- Powder
- Fruiting body extract
- Dual extract (water + alcohol)
- Spore oil
Safety
Common side effects
- GI upset
- Dizziness
- Dry mouth
Contraindications
- Bleeding disorders
- Before surgery
Products containing Reishi
Top-scoring supplements in our catalog that list Reishi on the label. Each product is graded on Formulate's ingredient-level rubric — dose accuracy, form, transparency, and third-party testing.
Evidence notes
Good immune and calming evidence
Grade B: Some human trials support key claims; further confirmation needed.
Reishi compared head-to-head
Related in Adaptogen
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Medical disclaimer. This page is educational and does not replace advice from a qualified healthcare provider. Individual needs and risks vary — consult a professional before starting, stopping, or combining supplements, especially if you are pregnant or nursing, taking medication, or managing a health condition.