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Herbal Extract

Royal Sun Blazei (Agaricus brasiliensis f. blazei)

Also known as: Agaricus brasiliensis, Agaricus blazei, ABM mushroom, himematsutake

D
Evidence

Royal Sun Blazei is a Brazilian medicinal mushroom rich in beta-glucans, traditionally used in Japanese and Brazilian folk medicine for immune support. Human evidence is very limited; studies are mostly small or preliminary.

Last reviewed June 2026 · Evidence graded from peer-reviewed research, not editorial opinion. Educational only — not medical advice.

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Primary uses

  • immune support
  • general wellness

How it works

  • beta-glucan-mediated immune activation
  • macrophage stimulation
  • potential anti-inflammatory effects

Dosage

Typical range
1,000–2,000 mg daily (dried mycelium biomass)
Timing
with meals for optimal absorption
With food
recommended
Duration
Limited data on optimal duration; generally considered safe for chronic use
Special populations
Pregnant/nursing women and immunocompromised patients should consult healthcare provider

Forms

  • mycelium biomass on rice· 70/100
  • extract· 70/100
  • powder· 70/100

Safety

Common side effects

  • rare: mild GI upset

Contraindications

  • immunosuppressant therapy (potential conflict)
  • autoimmune disease (immune stimulation may be problematic)

Evidence notes

Very limited human clinical data. Most evidence derives from in vitro and animal studies. A few small human studies exist but lack rigorous design. Requires further investigation.

Grade D: Primarily pre-clinical or anecdotal; human efficacy not established.

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Medical disclaimer. This page is educational and does not replace advice from a qualified healthcare provider. Individual needs and risks vary — consult a professional before starting, stopping, or combining supplements, especially if you are pregnant or nursing, taking medication, or managing a health condition.