Herbal Extract

Dihydromyricetin

Also known as: DHM, ampelopsin, Vine Tea Extract

Evidence

A flavonoid compound derived from Ampelopsis grossedentata (Vine Tea) traditionally used in Asian medicine. Preliminary research suggests potential benefits for alcohol metabolism and liver support.

Last reviewed June 2026 · Evidence graded from peer-reviewed research, not editorial opinion. Educational only — not medical advice.

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Primary uses

Alcohol metabolism support
Antioxidant support
Liver health

How it works

GABA receptor modulation
Antioxidant activity
Potential enhancement of alcohol clearance
Anti-inflammatory effects

Dosage

Typical range: 100-500 mg daily
Timing: With or before alcohol consumption for intended effects
With food: Can be taken with or without food
Duration: Typically used acutely around social occasions; long-term safety data limited
Special populations: Not recommended during pregnancy or lactation; limited pediatric data

Forms

Capsule· 70/100
Powder· 70/100
Extract· 70/100

Safety

Common side effects

Minimal reported; well-tolerated in studies

Contraindications

Pregnancy/lactation
Liver disease (consult healthcare provider)

Products containing Dihydromyricetin

Top-scoring supplements in our catalog that list Dihydromyricetin on the label. Each product is graded on Formulate's ingredient-level rubric — dose accuracy, form, transparency, and third-party testing.

Nootropics Depot

Alcohol Defense Capsule

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Evidence notes

Limited human clinical trials; mostly in-vitro and animal studies. Some evidence for alcohol-related outcomes, but human efficacy data remains preliminary.

Grade C: Mostly observational or small trials; mechanism is plausible but unproven at scale.

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Medical disclaimer. This page is educational and does not replace advice from a qualified healthcare provider. Individual needs and risks vary — consult a professional before starting, stopping, or combining supplements, especially if you are pregnant or nursing, taking medication, or managing a health condition.