Herbal Extract
Black Walnut Hulls Extract
Also known as: Black Walnut Hull, Juglans nigra hull, Walnut hull extract
Black walnut hulls are traditionally used in herbal medicine and contain juglone and polyphenols with antimicrobial and antioxidant properties. Limited clinical evidence supports most health claims, with most research conducted in vitro or in animal models.
Primary uses
- Digestive support
- Antimicrobial support
- Antioxidant support
- Traditional parasite cleanse
How it works
- Juglone compound exhibits antimicrobial activity against bacteria and fungi
- Polyphenol content may provide antioxidant effects
- Traditional use as antiparasitic agent
Dosage
- Typical range
- 200-500 mg daily (dried extract) or 1-2 ml tincture daily
- Timing
- With meals
- With food
- Recommended to take with food to minimize GI upset
- Duration
- Traditional use suggests 2-4 week cycles; avoid prolonged continuous use without medical supervision
- Special populations
- Avoid during pregnancy and lactation; use cautiously in children; consult healthcare provider if taking medications
Forms
- Liquid extract· 70/100
- Tincture· 70/100
- Powder· 70/100
- Capsule· 70/100
Safety
Common side effects
- Nausea
- Digestive upset
- Staining of teeth or tongue (dark discoloration)
- Allergic reactions in sensitized individuals
Contraindications
- Pregnancy and breastfeeding
- Hypersensitivity to Juglans species
- Severe GI conditions
- Concurrent use with iron supplements or iron-dependent medications (juglone may inhibit iron absorption)
Evidence notes
Most evidence is from traditional use and in vitro studies. Limited human clinical trials; mechanisms plausible but not well-validated in humans. Safety profile unclear with heavy use.
Grade C: Mostly observational or small trials; mechanism is plausible but unproven at scale.
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