Herbal Extract
Baikal Skullcap
Also known as: Scutellaria baicalensis, Chinese skullcap, baicalensis root, scute
Baikal skullcap is a traditional Chinese medicinal herb containing bioactive flavonoids (baicalin, wogonin) with preliminary evidence for anxiolytic, anti-inflammatory, and neuroprotective properties. Most human research remains limited, with effects primarily demonstrated in animal models and in vitro studies.
Last reviewed June 2026 · Evidence graded from peer-reviewed research, not editorial opinion. Educational only — not medical advice.
Every Baikal Skullcap product we have scored
| # | Product | Score | Per serving |
|---|---|---|---|
| 1 | Pure Encapsulations Th1 Support | 83 A- | $1.02 |
| 2 | Nutricost Baikal Skullcap Capsules | 82 A- | $0.10 |
| 3 | NOW Foods Liver Refresh | 76 B+ | $0.50 |
| 4 | Vital Nutrients ViraCon | 76 B+ | $1.32 |
| 5 | New Chapter Zyflamend Prostate | 73 B+ | $1.23 |
| 6 | New Chapter Zyflamend Nighttime | 70 B | $1.13 |
| 7 | New Chapter Turmeric Force Nighttime | 69 B | $1.13 |
| 8 | New Chapter Zyflamend Mini Softgels | 68 B | $1.53 |
Scored on dose accuracy, form, label transparency and third-party testing. Per-serving cost is list price divided by servings per container. No brand pays to be listed or ranked.
Common questions
How much Baikal Skullcap should I take?
The typical range is 500-2000 mg daily (dried root powder) or 300-600 mg standardized extract. Traditional use supports long-term consumption; optimal duration for specific benefits not established in human studies
When should I take Baikal Skullcap?
Can be taken with meals; traditionally consumed as decoction 2-3 times daily. No specific requirement; may take with or without food.
Which form of Baikal Skullcap is best?
Extract powder. Other forms in the catalog: Tablet, Capsule, Standardized extract, Powder, Capsules, Extract, Decoction.
Is Baikal Skullcap safe?
Commonly reported: Generally well-tolerated in traditional use, Rare: gastrointestinal upset, Rare: allergic reactions (uncommon).
Which Baikal Skullcap supplement scores highest?
Pure Encapsulations Th1 Support, at 83/100. Scored on dose accuracy, form, label transparency and third-party testing — no brand pays to be listed or ranked.
Primary uses
- Anxiety and stress support
- Sleep quality
- Inflammation management
- Neuroprotection
- Inflammation support
- Antioxidant support
- Traditional immune support
- Stress and relaxation
How it works
- Flavonoid compounds (baicalin, baicalein, wogonin) exhibit antioxidant activity
- May modulate inflammatory pathways and cytokine production
- Potential GABA receptor interaction (preliminary evidence)
Dosage
- Typical range
- 500-2000 mg daily (dried root powder) or 300-600 mg standardized extract
- Timing
- Can be taken with meals; traditionally consumed as decoction 2-3 times daily
- With food
- No specific requirement; may take with or without food
- Duration
- Traditional use supports long-term consumption; optimal duration for specific benefits not established in human studies
- Special populations
- Pregnancy/nursing: limited safety data; use with caution. Pediatric: insufficient evidence.
Forms
- Extract powder· 70/100
- Tablet· 70/100
- Capsule· 70/100
- Standardized extract· 70/100
- Capsules· 70/100
- Decoction· 70/100
Safety
Common side effects
- Generally well-tolerated in traditional use
- Rare: gastrointestinal upset
- Rare: allergic reactions (uncommon)
Contraindications
- Pregnancy and nursing (insufficient safety data)
- Severe liver disease (use with caution)
- Known hypersensitivity to Scutellaria species
Products containing Baikal Skullcap
Top-scoring supplements in our catalog that list Baikal Skullcap on the label. Each product is graded on Formulate's ingredient-level rubric — dose accuracy, form, transparency, and third-party testing.
Evidence notes
Substantial in vitro and animal model data supports anti-inflammatory and antioxidant effects; human clinical trials are sparse and often low-quality. Traditional use is well-documented, but modern RCT evidence in humans is limited. Grade reflects moderate/preliminary human evidence.
Grade C: Mostly observational or small trials; mechanism is plausible but unproven at scale.
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Medical disclaimer. This page is educational and does not replace advice from a qualified healthcare provider. Individual needs and risks vary — consult a professional before starting, stopping, or combining supplements, especially if you are pregnant or nursing, taking medication, or managing a health condition.