Herbal Extract
Citrus Bergamot Extract
Also known as: Citrus bergamia, Bergamot fruit extract, Bergamot polyphenol extract, BPF
Citrus bergamot is a citrus fruit rich in flavonoids and polyphenols, primarily studied for potential cardiovascular and lipid-modulating effects. Limited human clinical evidence supports use for cholesterol and triglyceride management, though most research is preliminary.
Primary uses
- Cholesterol management
- Triglyceride support
- Cardiovascular health
- Antioxidant support
How it works
- Flavonoid and polyphenol content may modulate lipid metabolism
- Potential HMG-CoA reductase inhibition
- Antioxidant and anti-inflammatory effects
Dosage
- Typical range
- 500–1500 mg daily of extract
- Timing
- With meals for absorption
- With food
- Recommended; fat-soluble polyphenols absorb better with food
- Duration
- Most studies used 8–12 week durations; long-term safety data limited
- Special populations
- Pregnant/nursing women should consult healthcare provider; may interact with statin medications
Forms
- Extract powder· 70/100
- Capsules· 70/100
- Concentrated extract (25:1 ratio)· 70/100
Safety
Common side effects
- Generally well-tolerated
- Mild gastrointestinal upset possible
- Rare headache reports
Contraindications
- Concurrent use with statin drugs (potential synergistic effect; medical supervision recommended)
- Pregnancy/nursing (insufficient safety data)
Evidence notes
Most human evidence is small, preliminary, or short-duration. Some positive results for lipid profiles in limited RCTs, but insufficient high-quality evidence for strong recommendations. Effect sizes modest when present.
Grade C: Mostly observational or small trials; mechanism is plausible but unproven at scale.
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