Herbal Extract
Mangosteen Extract (Garcinia mangostana)
Also known as: Garcinia mangostana fruit extract, mangosteen fruit powder, mangosteen pericarp extract
Mangosteen fruit extract is rich in xanthones and polyphenolic compounds with antioxidant properties, though human clinical evidence for health benefits remains limited. Most evidence comes from in vitro and animal studies rather than controlled human trials.
Last reviewed June 2026 · Evidence graded from peer-reviewed research, not editorial opinion. Educational only — not medical advice.
Primary uses
- Antioxidant support
- Anti-inflammatory support
- General wellness
How it works
- Xanthone polyphenols may act as antioxidants
- Potential anti-inflammatory effects via polyphenol content
- Free radical scavenging activity (in vitro)
Dosage
- Typical range
- 400–800 mg daily (extract form)
- Timing
- With meals
- With food
- May improve absorption and reduce GI upset
- Duration
- No established optimal duration; typically used long-term for general wellness
- Special populations
- Safety in pregnancy/lactation not well-established; consult healthcare provider
Forms
- Powder· 70/100
- Extract· 70/100
- Capsule· 70/100
Safety
Common side effects
- Generally well-tolerated
- Mild GI upset (rare)
- Headache (rare)
Contraindications
- Pregnancy and lactation (insufficient safety data)
- History of allergies to Garcinia species
Evidence notes
Limited human RCT data; most evidence is from in vitro and animal models. A few small human studies exist but are insufficient for strong evidence classification. Well-tolerated traditional fruit with phytochemical profile, but efficacy claims require more rigorous clinical investigation.
Grade C: Mostly observational or small trials; mechanism is plausible but unproven at scale.
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Medical disclaimer. This page is educational and does not replace advice from a qualified healthcare provider. Individual needs and risks vary — consult a professional before starting, stopping, or combining supplements, especially if you are pregnant or nursing, taking medication, or managing a health condition.