Herbal Extract
Ganoderma lucidum Extract (Fruiting Body)
Also known as: Reishi, Red Reishi, Lingzhi, Ganoderma extract
Ganoderma lucidum (reishi) is a medicinal mushroom used traditionally in Asian medicine for stress and immune support. Modern research shows modest evidence for stress reduction and sleep quality, though study quality and standardization remain inconsistent.
Last reviewed June 2026 · Evidence graded from peer-reviewed research, not editorial opinion. Educational only — not medical advice.
Primary uses
- Stress and anxiety reduction
- Sleep quality improvement
- Immune system support
- Relaxation and adaptogenic effects
How it works
- Bioactive polysaccharides and beta-glucans may modulate immune function
- Triterpenes (luciderol, ganoderiol) may have sedative and anxiolytic properties
- Potential modulation of stress hormones (cortisol) and HPA axis
Dosage
- Typical range
- 1.5–3 g daily (extract); 1:1 extracts typically 1–3 g daily
- Timing
- Evening for sleep support; can be taken anytime for general stress management
- With food
- May be taken with or without food; fat may enhance absorption of lipophilic compounds
- Duration
- Benefits often emerge after 2–4 weeks of consistent use
- Special populations
- Safe for most adults; pregnant/nursing women should consult provider
Forms
- Powder (1:1 extract)· 70/100
- Capsule· 70/100
- Tincture· 70/100
- Whole fruiting body· 70/100
- Standardized extract· 70/100
Safety
Common side effects
- Mild gastrointestinal upset
- Dizziness or dry mouth (rare)
- Insomnia if taken in excess or too late in day
Contraindications
- Bleeding disorders (may have mild anticoagulant effects)
- Scheduled surgery (discontinue 2 weeks prior)
- Immunosuppressive therapy (theoretical concern; consult physician)
Products containing Ganoderma lucidum Extract (Fruiting Body)
Top-scoring supplements in our catalog that list Ganoderma lucidum Extract (Fruiting Body) on the label. Each product is graded on Formulate's ingredient-level rubric — dose accuracy, form, transparency, and third-party testing.
See all products →Evidence notes
Multiple human studies suggest benefits for anxiety and sleep, but methodological quality is often poor, sample sizes modest, and standardization of extracts varies widely. Fruiting body extracts show more promising data than mycelium. Insufficient evidence for strong A or B grade.
Grade C: Mostly observational or small trials; mechanism is plausible but unproven at scale.
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Medical disclaimer. This page is educational and does not replace advice from a qualified healthcare provider. Individual needs and risks vary — consult a professional before starting, stopping, or combining supplements, especially if you are pregnant or nursing, taking medication, or managing a health condition.

