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Sleep

Honokiol

Also known as: Magnolia bark extract (isolated)

B
Evidence

Isolated magnolia bark compound with potent GABA-A effects. More specific than whole bark.

Primary uses

  • Anxiety relief
  • Sleep support
  • Neuroprotection

How it works

  • Potent GABA-A positive modulator
  • Brain antioxidant
  • Anti-inflammatory

Dosage

Typical range
50-200mg
Timing
Evening or as needed
With food
Either
Duration
Safe for regular use
Special populations
Anxiety, sleep

Forms

  • Capsule

Safety

Common side effects

  • Drowsiness
  • Mild sedation

Contraindications

  • Pregnancy

Evidence notes

Active compound from magnolia bark

Grade B: Some human trials support key claims; further confirmation needed.

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Medical disclaimer. This page is educational and does not replace advice from a qualified healthcare provider.