Sleep
Honokiol
Also known as: Magnolia bark extract (isolated)
Isolated magnolia bark compound with potent GABA-A effects. More specific than whole bark.
Last reviewed June 2026 · Evidence graded from peer-reviewed research, not editorial opinion. Educational only — not medical advice.
Every Honokiol product we have scored
| # | Product | Score | Per serving |
|---|---|---|---|
| 1 | BulkSupplements Magnolia Extract Powder | 88 A | $0.08 |
| 2 | Integrative Therapeutics Pro-Som | 80 A- | $2.87 |
| 3 | Integrative Therapeutics ProThrivers Wellness Sleep | 68 B | $0.45 |
Scored on dose accuracy, form, label transparency and third-party testing. Per-serving cost is list price divided by servings per container. No brand pays to be listed or ranked.
Common questions
How much Honokiol should I take?
The typical range is 50-200mg. Safe for regular use
When should I take Honokiol?
Evening or as needed. Either.
Which form of Honokiol is best?
Capsule — Isolated compound.
Is Honokiol safe?
Commonly reported: Drowsiness, Mild sedation. Serious warnings: Potent - start low. No concerns
Which Honokiol supplement scores highest?
BulkSupplements Magnolia Extract Powder, at 88/100. Scored on dose accuracy, form, label transparency and third-party testing — no brand pays to be listed or ranked.
Primary uses
- Anxiety relief
- Sleep support
- Neuroprotection
How it works
- Potent GABA-A positive modulator
- Brain antioxidant
- Anti-inflammatory
Dosage
- Typical range
- 50-200mg
- Timing
- Evening or as needed
- With food
- Either
- Duration
- Safe for regular use
- Special populations
- Anxiety, sleep
Forms
- Capsule
Safety
Common side effects
- Drowsiness
- Mild sedation
Contraindications
- Pregnancy
Products containing Honokiol
Top-scoring supplements in our catalog that list Honokiol on the label. Each product is graded on Formulate's ingredient-level rubric — dose accuracy, form, transparency, and third-party testing.
Evidence notes
Active compound from magnolia bark
Grade B: Some human trials support key claims; further confirmation needed.
Related in Sleep
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Medical disclaimer. This page is educational and does not replace advice from a qualified healthcare provider. Individual needs and risks vary — consult a professional before starting, stopping, or combining supplements, especially if you are pregnant or nursing, taking medication, or managing a health condition.