Cardiovascular
Diosmin/Hesperidin
Also known as: Micronized diosmin, Daflon
Citrus flavonoids for venous and lymphatic health. Popular in Europe for vein support.
Last reviewed June 2026 · Evidence graded from peer-reviewed research, not editorial opinion. Educational only — not medical advice.
Primary uses
- Venous health
- Hemorrhoids
- Leg swelling
- Lymphatic
How it works
- Strengthens vein walls
- Improves lymphatic drainage
- Anti-inflammatory
Dosage
- Typical range
- 500-1000mg daily
- Timing
- With meals
- With food
- Yes
- Duration
- Ongoing or cycling
- Special populations
- Venous insufficiency, hemorrhoids, swelling
Forms
- Micronized
- With hesperidin
Safety
Common side effects
- GI upset
- Headache
Contraindications
- None
Evidence notes
European venous medication
Grade A: Multiple well-designed human trials support the main claims.
Related in Cardiovascular
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Medical disclaimer. This page is educational and does not replace advice from a qualified healthcare provider. Individual needs and risks vary — consult a professional before starting, stopping, or combining supplements, especially if you are pregnant or nursing, taking medication, or managing a health condition.