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Cardiovascular

Horse Chestnut Extract

Also known as: Aesculus hippocastanum, Aescin, Horse Chestnut Extract (Aesculus hippocastanum), Aesculus hippocastanum seed extract

A
Evidence

Horse chestnut extract, standardized to escin, is traditionally used to support venous circulation and reduce symptoms of chronic venous insufficiency. Multiple clinical trials support its efficacy for reducing leg swelling, heaviness, and pain related to venous dysfunction.

Primary uses

  • Venous insufficiency
  • Leg swelling
  • Varicose veins
  • Circulation
  • Venous insufficiency support
  • Leg swelling and edema reduction
  • Circulatory health
  • Leg heaviness and discomfort

How it works

  • Strengthens vein walls
  • Reduces capillary permeability
  • Anti-inflammatory

Dosage

Typical range
300mg extract with 50-100mg aescin daily
Timing
Divided doses
With food
Yes
Duration
Ongoing for vein support
Special populations
Venous insufficiency, heavy legs, standing jobs

Forms

  • Standardized extract
  • Powder extract· 70/100
  • Standardized extract capsules· 70/100
  • Topical gel· 70/100

Safety

Common side effects

  • GI upset
  • Itching

Contraindications

  • Kidney disease
  • Liver disease

Evidence notes

Strong evidence for venous insufficiency

Grade A: Multiple well-designed human trials support the main claims.

Related in Cardiovascular

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Medical disclaimer. This page is educational and does not replace advice from a qualified healthcare provider.