Immune
Beta Glucan 1,3/1,6 (from Saccharomyces cerevisiae)
Also known as: Baker's yeast beta-glucan, Yeast beta-glucan, β-glucan 1,3/1,6, Saccharomyces cerevisiae beta-glucan
Beta-glucan 1,3/1,6 from baker's yeast is a soluble polysaccharide that may support immune function by enhancing natural killer cell activity and promoting a healthy inflammatory response. Moderate clinical evidence supports its use for general immune support, particularly during periods of stress or seasonal challenges.
Last reviewed June 2026 · Evidence graded from peer-reviewed research, not editorial opinion. Educational only — not medical advice.
Every Beta Glucan 1,3/1,6 (from Saccharomyces cerevisiae) product we have scored
| # | Product | Score | Per serving |
|---|---|---|---|
| 1 | SmartyPants Kids Probiotic & Prebiotic - Grape | 78 B+ | $0.87 |
| 2 | SmartyPants Kids Probiotic & Prebiotic - Strawberry | 78 B+ | $0.87 |
Scored on dose accuracy, form, label transparency and third-party testing. Per-serving cost is list price divided by servings per container. No brand pays to be listed or ranked.
Common questions
How much Beta Glucan 1,3/1,6 (from Saccharomyces cerevisiae) should I take?
The typical range is 250-500 mg daily. Consistent daily use for 4+ weeks may be needed for optimal immune support effects
When should I take Beta Glucan 1,3/1,6 (from Saccharomyces cerevisiae)?
With meals or as directed on label. May enhance absorption; typically taken with food.
Which form of Beta Glucan 1,3/1,6 (from Saccharomyces cerevisiae) is best?
Capsules. Other forms in the catalog: Tablets, Powder.
Is Beta Glucan 1,3/1,6 (from Saccharomyces cerevisiae) safe?
Commonly reported: Rare mild gastrointestinal effects (nausea, digestive changes), Mild headache in isolated cases.
Which Beta Glucan 1,3/1,6 (from Saccharomyces cerevisiae) supplement scores highest?
SmartyPants Kids Probiotic & Prebiotic - Grape, at 78/100. Scored on dose accuracy, form, label transparency and third-party testing — no brand pays to be listed or ranked.
Primary uses
- Immune system support
- Natural killer cell activation
- Inflammatory response modulation
- General wellness
How it works
- Binds to pattern recognition receptors (Dectin-1) on innate immune cells
- Stimulates macrophage and natural killer cell activity
- Enhances complement pathway activation
- Modulates cytokine production
Dosage
- Typical range
- 250-500 mg daily
- Timing
- With meals or as directed on label
- With food
- May enhance absorption; typically taken with food
- Duration
- Consistent daily use for 4+ weeks may be needed for optimal immune support effects
- Special populations
- Generally recognized as safe for most adults; limited data in pregnancy/lactation
Forms
- Capsules· 70/100
- Tablets· 70/100
- Powder· 70/100
Safety
Common side effects
- Rare mild gastrointestinal effects (nausea, digestive changes)
- Mild headache in isolated cases
Contraindications
- Severe immunocompromised states (immunosuppressive therapy) — may cause excessive immune activation; consult healthcare provider
- Known baker's yeast allergy or sensitivity
Products containing Beta Glucan 1,3/1,6 (from Saccharomyces cerevisiae)
Top-scoring supplements in our catalog that list Beta Glucan 1,3/1,6 (from Saccharomyces cerevisiae) on the label. Each product is graded on Formulate's ingredient-level rubric — dose accuracy, form, transparency, and third-party testing.
Evidence notes
Multiple RCTs demonstrate immune-supportive effects, particularly for NK cell activity and respiratory health in stressed populations. However, variation in extraction methods and dosing protocols limits generalizability; most robust data exists for specific yeast beta-glucan preparations.
Grade B: Some human trials support key claims; further confirmation needed.
Related in Immune
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Medical disclaimer. This page is educational and does not replace advice from a qualified healthcare provider. Individual needs and risks vary — consult a professional before starting, stopping, or combining supplements, especially if you are pregnant or nursing, taking medication, or managing a health condition.