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Immune

Turkey Tails Mycelium

Also known as: Trametes versicolor, Coriolus versicolor, Polypore mushroom, Yun Zhi

B
Evidence

Turkey Tails mycelium is rich in polysaccharides (particularly PSK and PSP) with established traditional use in Asia and growing clinical research for immune and gastrointestinal health. Several human studies support benefits for immune function.

Last reviewed June 2026 · Evidence graded from peer-reviewed research, not editorial opinion. Educational only — not medical advice.

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Primary uses

  • Immune support
  • Gut health
  • Gastrointestinal microbiota support

How it works

  • PSK and PSP polysaccharides activate immune cells
  • β-glucan signaling
  • Prebiotic effect supporting beneficial bacteria

Dosage

Typical range
1,500-3,000 mg daily (mycelium form); 3-9 grams daily if PSK/PSP standardized
Timing
With meals
With food
Recommended
Duration
Designed for consistent long-term use; benefits may accumulate over weeks
Special populations
Generally safe; immunocompromised patients should consult healthcare provider

Forms

  • Mycelium on rice biomass· 70/100
  • Fruiting body extract· 70/100
  • Standardized PSK/PSP extract· 70/100
  • Capsule· 70/100

Safety

Common side effects

  • Rare: mild digestive changes
  • Rare: headache during initial use

Contraindications

  • Mushroom allergies
  • Severe immunocompromise (medical supervision recommended)

Evidence notes

Strong evidence from multiple human studies, particularly from Asia, for immune-modulating effects. PSK (polysaccharide-K) is studied as adjunctive in oncology. Evidence quality is good but Western RCTs could be more robust.

Grade B: Some human trials support key claims; further confirmation needed.

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Medical disclaimer. This page is educational and does not replace advice from a qualified healthcare provider. Individual needs and risks vary — consult a professional before starting, stopping, or combining supplements, especially if you are pregnant or nursing, taking medication, or managing a health condition.