Immune
Turkey Tails Mycelium
Also known as: Trametes versicolor, Coriolus versicolor, Polypore mushroom, Yun Zhi
Turkey Tails mycelium is rich in polysaccharides (particularly PSK and PSP) with established traditional use in Asia and growing clinical research for immune and gastrointestinal health. Several human studies support benefits for immune function.
Primary uses
- Immune support
- Gut health
- Gastrointestinal microbiota support
How it works
- PSK and PSP polysaccharides activate immune cells
- β-glucan signaling
- Prebiotic effect supporting beneficial bacteria
Dosage
- Typical range
- 1,500-3,000 mg daily (mycelium form); 3-9 grams daily if PSK/PSP standardized
- Timing
- With meals
- With food
- Recommended
- Duration
- Designed for consistent long-term use; benefits may accumulate over weeks
- Special populations
- Generally safe; immunocompromised patients should consult healthcare provider
Forms
- Mycelium on rice biomass· 70/100
- Fruiting body extract· 70/100
- Standardized PSK/PSP extract· 70/100
- Capsule· 70/100
Safety
Common side effects
- Rare: mild digestive changes
- Rare: headache during initial use
Contraindications
- Mushroom allergies
- Severe immunocompromise (medical supervision recommended)
Evidence notes
Strong evidence from multiple human studies, particularly from Asia, for immune-modulating effects. PSK (polysaccharide-K) is studied as adjunctive in oncology. Evidence quality is good but Western RCTs could be more robust.
Grade B: Some human trials support key claims; further confirmation needed.
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