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Thorne Methyl-Guard®

Methyl-Guard®

93Score
Grade A · capsule · 60 servings · $56.00

Methyl-Guard® scores 93/100 (A grade). Strengths: 3 Grade A, 1 Grade B ingredients.

B-ComplexHeart HealthMethylationBrain Health

Score Breakdown

Formulate scores every product across six weighted dimensions. Each dimension is graded independently — hover or tap to see what drove each component.

Evidence Qualityweight 25%
96/ 100
Dose Accuracyweight 20%
95/ 100
Bioavailabilityweight 20%
96/ 100
Transparencyweight 10%
100/ 100
Safetyweight 10%
94/ 100
Manufacturingweight 10%
80/ 100
Valueweight 5%
90/ 100

Ingredients per Serving

IngredientAmount
Betaine Anhydrous (Trimethylglycine)1.8 g
Vitamin B12 (as Methylcobalamin)1.2 mg
Vitamin B6 (as Pyridoxal 5'-Phosphate)20.4 mg
Folate (L-5-MTHF)2 mg DFE

Certifications & Testing

NSF CertifiedGluten FreeDairy FreeSoy FreeThorne VerifiedNatural FlavorsNatural ColorsGMP Certified

Other Ingredients

Calcium (Citrate), Calcium Laurate, Hypromellose Capsule, Silicon Dioxide

Recommended Use

Take 3 capsules two times daily or as recommended by your health-care practitioner.

Warnings

ALLERGY WARNING This product is contraindicated in an individual with a history of hypersensitivity to any of its ingredients. PREGNANCY If pregnant, consult your health-care practitioner before using this product. INTERACTIONS 5-methyltetrahydrofolate (5-MTHF) supplementation is not recommended concurrent with methotrexate cancer therapy, as it can interfere with methotrexate's anti-neoplastic ac

Frequently Asked Questions

What is Thorne Methyl-Guard®'s Formulate score?

Thorne Methyl-Guard® scores 93 out of 100 (grade A) on Formulate's ingredient-level rubric, which weighs evidence quality, dose accuracy, bioavailability, transparency, safety, and manufacturing practices.

What's in Thorne Methyl-Guard®?

Each serving contains Betaine Anhydrous (Trimethylglycine) (1.8 g), Vitamin B12 (as Methylcobalamin) (1.2 mg), Vitamin B6 (as Pyridoxal 5'-Phosphate) (20.4 mg), Folate (L-5-MTHF) (2 mg DFE). Serving size: 3 Capsules. 60 servings per container.

How do I take methyl-guard®?

Take 3 capsules two times daily or as recommended by your health-care practitioner.

Is Thorne Methyl-Guard® third-party tested?

Thorne lists the following certifications and testing for this product: NSF Certified, Gluten Free, Dairy Free, Soy Free, Thorne Verified, Natural Flavors, Natural Colors, GMP Certified.

Related Supplements

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Disclosure. Formulate may earn a commission from purchases made through links on this page. Commissions never influence scores — every product is graded by the same automated rubric. This page is for educational purposes only and does not replace advice from a qualified healthcare provider.