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vitamin d and vitamin k2

Vitamin D and K2 work synergistically

What's happening

Vitamin D increases calcium absorption, while K2 directs calcium to bones and away from arteries. Together they optimize bone health and reduce cardiovascular calcification risk.

Recommendation

Take D3 with K2, especially at higher vitamin D doses (>2000 IU).

Timing

Take together, ideally with a fat-containing meal

Sources

  • International Journal of Endocrinology
  • Nutrients

Frequently Asked Questions

Can I take vitamin d and vitamin k2 together?

Vitamin D and K2 work synergistically. Take D3 with K2, especially at higher vitamin D doses (>2000 IU).

How should I time vitamin d and vitamin k2?

Take together, ideally with a fat-containing meal

Is this interaction dangerous?

This interaction is rated “Synergy” by Formulate. Vitamin D increases calcium absorption, while K2 directs calcium to bones and away from arteries. Together they optimize bone health and reduce cardiovascular calcification risk.

Want to check your whole stack?

The free checker lets you add any combination of supplements and medications at once. Formulate's desktop app goes further — every stack change surfaces interaction alerts automatically.

Medical disclaimer. This page is for educational purposes only and does not replace advice from a qualified healthcare provider.