Primary Research · 2019

Vitamin D Supplements and Prevention of Cancer and Cardiovascular Disease

Manson et al. · New England Journal of Medicine, 2019

Key finding

VITAL trial (n=25,871). 2,000 IU/day D3 did not significantly reduce cancer incidence or cardiovascular events in a generally replete population.

Read the paper

Open on PubMed

https://pubmed.ncbi.nlm.nih.gov/30415629/

Cited in 1 guide

Roundup
Best Vitamin D Supplements 2026: Ranked by Clinical Evidence
42% of adults are deficient. Learn which D3 form, dose, and brand actually raises blood levels — with cofactor guidance and lab-verified picks.

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