Mineral
Zinc Carnosine
Also known as: PepZin GI, Polaprezinc, Zinc Carnosine (Zinc-L-Carnosine), Zinc-L-carnosine
Specialized zinc compound for gut health. Supports stomach lining and is used for gastritis, ulcers, and leaky gut.
Last reviewed June 2026 · Evidence graded from peer-reviewed research, not editorial opinion. Educational only — not medical advice.
Primary uses
- Gut health
- Stomach lining
- Gastritis/ulcers
- Gut barrier
How it works
- Adheres to ulcerated tissue
- Stimulates mucus secretion
- Antioxidant protection
Dosage
- Typical range
- 75-150 mg twice daily
- Timing
- Between meals or before bed
- With food
- Between meals optimal
- Duration
- 8 weeks typical
- Special populations
- Gastritis, GERD, leaky gut
Forms
- Capsule
Safety
Common side effects
- Very well tolerated
Contraindications
- None specific
Known interactions
- Warningwith zinc
Zinc depletes copper over time
- Cautionwith zinc
Zinc and iron compete for absorption
- Cautionwith calcium
Calcium may reduce zinc absorption
- Infowith magnesium
High-dose magnesium may slightly reduce zinc absorption
- Synergywith zinc
Quercetin acts as zinc ionophore
- Synergywith zinc
Zinc needed for vitamin A metabolism
Evidence notes
Strong gastroprotective evidence
Grade A: Multiple well-designed human trials support the main claims.
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Medical disclaimer. This page is educational and does not replace advice from a qualified healthcare provider. Individual needs and risks vary — consult a professional before starting, stopping, or combining supplements, especially if you are pregnant or nursing, taking medication, or managing a health condition.