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Antioxidant

Vitexin + Isovitexin Isoflavones

Also known as: Vitexin, Isovitexin, C-glucosyl flavone

C
Evidence

Vitexin and isovitexin are flavonoid compounds (specifically C-glycosyl flavones) with antioxidant properties found in various plants. In vitro and animal evidence suggests potential neuroprotective and anti-inflammatory effects, though human clinical data is limited.

Last reviewed June 2026 · Evidence graded from peer-reviewed research, not editorial opinion. Educational only — not medical advice.

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Primary uses

  • Antioxidant support
  • Potential neuroprotection
  • Anti-inflammatory support

How it works

  • Free radical scavenging
  • Antioxidant enzyme upregulation
  • Potential GABA modulation (in vitro)

Dosage

Typical range
Typically 50-500 mg daily (as part of combination products)
Timing
With meals
With food
Recommended; may improve absorption
Duration
No established optimal duration; generally safe for prolonged use
Special populations
Insufficient data in pregnancy/lactation; use cautiously

Forms

  • Standardized extract· 70/100
  • Combination product· 70/100

Safety

Evidence notes

Primary evidence is from in vitro and animal models; human clinical trials are scarce or absent. Bioavailability and physiological relevance in humans unclear.

Grade C: Mostly observational or small trials; mechanism is plausible but unproven at scale.

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Medical disclaimer. This page is educational and does not replace advice from a qualified healthcare provider. Individual needs and risks vary — consult a professional before starting, stopping, or combining supplements, especially if you are pregnant or nursing, taking medication, or managing a health condition.