Antioxidant
Quercetin Dihydrate (from Sophora japonica bud extract)
Also known as: quercetin, quercetin dihydrate, sophora quercetin
A plant-derived bioflavonoid extracted from Sophora japonica buds with potent antioxidant and anti-inflammatory properties. Quercetin is one of the most abundant flavonoids in plant foods.
Last reviewed June 2026 · Evidence graded from peer-reviewed research, not editorial opinion. Educational only — not medical advice.
Every Quercetin Dihydrate (from Sophora japonica bud extract) product we have scored
| # | Product | Score | Per serving |
|---|---|---|---|
| 1 | Thorne Quercetin Phytosome | 92 A | $0.77 |
| 2 | Thorne Quercetin Complex | 90 A | $0.90 |
| 3 | Thorne Advanced Nutrients | 88 A | $2.40 |
| 4 | Thorne Pre-Workout Elite | 88 A | $1.83 |
| 5 | Thorne PolyResveratrol-SR® | 87 A | $1.97 |
| 6 | Nutricost Quercetin (1000mg) | 87 A | $0.37 |
| 7 | Pure Encapsulations PureDefense with NAC | 87 A | $1.90 |
| 8 | Pure Encapsulations Quercetin | 86 A- | $0.97 |
| 9 | Pure Encapsulations NeuroPure | 86 A- | $1.18 |
| 10 | Jarrow Formulas Quercetin | 86 A- | $0.34 |
| 11 | Pure Encapsulations A.I. Formula | 85 A- | $0.61 |
| 12 | Thorne ResveraCel | 84 A- | $2.00 |
Scored on dose accuracy, form, label transparency and third-party testing. Per-serving cost is list price divided by servings per container. No brand pays to be listed or ranked.
Common questions
How much Quercetin Dihydrate (from Sophora japonica bud extract) should I take?
The typical range is 250–1000 mg daily, often split into 2–3 doses. Safe for continuous use; effects may accumulate over weeks
When should I take Quercetin Dihydrate (from Sophora japonica bud extract)?
With meals for improved absorption. With food; bioavailability enhanced by fat or quercetin transporters.
Which form of Quercetin Dihydrate (from Sophora japonica bud extract) is best?
powder. Other forms in the catalog: capsule, dihydrate.
Is Quercetin Dihydrate (from Sophora japonica bud extract) safe?
Commonly reported: Rare; headache or stomach upset at high doses.
Which Quercetin Dihydrate (from Sophora japonica bud extract) supplement scores highest?
Thorne Quercetin Phytosome, at 92/100. Scored on dose accuracy, form, label transparency and third-party testing — no brand pays to be listed or ranked.
Primary uses
- Antioxidant support
- Anti-inflammatory response
- Seasonal allergy support
- Immune modulation
How it works
- Mast cell stabilization
- Quercetin may reduce histamine release
- Free radical scavenging
- NF-κB pathway modulation
Dosage
- Typical range
- 250–1000 mg daily, often split into 2–3 doses
- Timing
- With meals for improved absorption
- With food
- With food; bioavailability enhanced by fat or quercetin transporters
- Duration
- Safe for continuous use; effects may accumulate over weeks
- Special populations
- Generally safe; those on blood thinners should monitor with healthcare provider
Forms
- powder· 70/100
- capsule· 70/100
- dihydrate· 70/100
Safety
Common side effects
- Rare; headache or stomach upset at high doses
Contraindications
- Caution with anticoagulant/antiplatelet medications
Products containing Quercetin Dihydrate (from Sophora japonica bud extract)
Top-scoring supplements in our catalog that list Quercetin Dihydrate (from Sophora japonica bud extract) on the label. Each product is graded on Formulate's ingredient-level rubric — dose accuracy, form, transparency, and third-party testing.
Evidence notes
Good evidence for antioxidant and anti-inflammatory effects; moderate evidence for seasonal allergy support. Bioavailability improved with dihydrate form.
Grade B: Some human trials support key claims; further confirmation needed.
Cited research for Quercetin Dihydrate (from Sophora japonica bud extract)
Clinical studies referenced across Formulate guides that mention quercetin dihydrate (from sophora japonica bud extract). Each links to the full study page with PubMed source + the guides that cite it.
Related in Antioxidant
Check a full stack
Formulate's free interaction checker lets you paste in any combination of supplements and medications at once — every pairing flags severity, timing, and cited evidence.
Open the checkerWhere does Quercetin Dihydrate (from Sophora japonica bud extract) fit in your stack?
Answer two questions and get a stack graded on research — every ingredient scored on the evidence behind it, not the marketing.
Build my stack2 questions · free · no account needed to start
Also on iPhone — get the free app
Evidence-based supplement guides, no spam
We send a short digest when new guides drop — nothing else. No affiliate pushes, no sponsored content, unsubscribe anytime.
Medical disclaimer. This page is educational and does not replace advice from a qualified healthcare provider. Individual needs and risks vary — consult a professional before starting, stopping, or combining supplements, especially if you are pregnant or nursing, taking medication, or managing a health condition.