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Protein

SBI (Serum-Derived Bovine Immunoglobulins)

Also known as: SBI, EnteraGam, Bovine immunoglobulins

B
Evidence

Concentrated immunoglobulins that bind pathogens and toxins in the gut, supporting barrier function.

Last reviewed June 2026 · Evidence graded from peer-reviewed research, not editorial opinion. Educational only — not medical advice.

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Primary uses

  • Gut barrier
  • IBS-D
  • Enteropathy
  • Immune support

How it works

  • Binds pathogens and toxins
  • Supports gut barrier
  • Reduces inflammation
  • Improves nutrient absorption

Dosage

Typical range
5-10g daily (medical food) or as directed
Timing
With meals
With food
Yes
Duration
Ongoing for chronic conditions
Special populations
IBS-D, enteropathy, HIV enteropathy, difficult GI cases

Forms

  • Powder
  • Capsules

Safety

Common side effects

  • Mild GI symptoms initially

Contraindications

  • Severe milk allergy (though different from milk proteins)

Evidence notes

Growing clinical evidence for gut conditions

Grade B: Some human trials support key claims; further confirmation needed.

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Medical disclaimer. This page is educational and does not replace advice from a qualified healthcare provider. Individual needs and risks vary — consult a professional before starting, stopping, or combining supplements, especially if you are pregnant or nursing, taking medication, or managing a health condition.