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Protein

Lactoferrin

Also known as: Apolactoferrin, Bovine lactoferrin, LF

B
Evidence

Iron-binding protein from milk with antimicrobial, antiviral, and immune-modulating properties. Supports gut and systemic immunity.

Last reviewed June 2026 · Evidence graded from peer-reviewed research, not editorial opinion. Educational only — not medical advice.

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Primary uses

  • Antimicrobial
  • Immune modulation
  • Iron regulation
  • Gut immunity

How it works

  • Binds iron, starving pathogens
  • Direct antimicrobial activity
  • Modulates immune cell activity
  • Enhances gut barrier function

Dosage

Typical range
100-300mg daily
Timing
Empty stomach or between meals
With food
Empty stomach may be optimal
Duration
Daily for immune support
Special populations
Those with recurrent infections, gut issues

Forms

  • Bovine lactoferrin
  • Apolactoferrin

Safety

Common side effects

  • Rare, well tolerated
  • Mild GI upset possible

Contraindications

  • Milk/dairy allergy (bovine source)

Evidence notes

Promising research, especially for gut and immunity

Grade B: Some human trials support key claims; further confirmation needed.

Related in Protein

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Medical disclaimer. This page is educational and does not replace advice from a qualified healthcare provider. Individual needs and risks vary — consult a professional before starting, stopping, or combining supplements, especially if you are pregnant or nursing, taking medication, or managing a health condition.