Mineral
Selenium (Selenomethionine)
Also known as: L-selenomethionine, Organic selenium
A
Evidence
Highly bioavailable organic selenium for thyroid and antioxidant function. Narrow optimal range requires careful dosing.
Primary uses
- Thyroid support
- Glutathione system
- Immune function
How it works
- Incorporated into selenoproteins
- Essential for T4 to T3 conversion
- Supports glutathione peroxidase
Dosage
- Typical range
- 100-200 mcg daily
- Timing
- Any
- With food
- Optional
- Duration
- Don't exceed 400 mcg
- Special populations
- Thyroid patients
Forms
- Selenomethionine
- Selenium yeast
Safety
Common side effects
- Garlic breath at high doses
Contraindications
- High selenium status
Evidence notes
Well-established for thyroid and antioxidant
Grade A: Multiple well-designed human trials support the main claims.
Related in Mineral
Check a full stack
Formulate's free interaction checker lets you paste in any combination of supplements and medications at once — every pairing flags severity, timing, and cited evidence.
Open the checkerMedical disclaimer. This page is educational and does not replace advice from a qualified healthcare provider.