Hormone Support
Pregnenolone
Also known as: Mother hormone, PREG, Steroid precursor
C
Evidence
Precursor hormone supporting overall steroid hormone production including cortisol.
Primary uses
- Hormone support
- Cognitive function
- Mood
- Memory
- HPA axis support
- Hormone balance
- Cognition
How it works
- Precursor to all steroid hormones
- Neurosteroid with brain effects
- Modulates GABA and NMDA
Dosage
- Typical range
- 5-50mg daily
- Timing
- Morning
- With food
- With fat
- Duration
- Cycle recommended
- Special populations
- Age-related decline
Forms
- Capsule
- Micronized
Safety
Common side effects
- Irritability
- Acne
- Hair changes
Contraindications
- Hormone-sensitive cancers
Evidence notes
Limited clinical evidence
Grade C: Mostly observational or small trials; mechanism is plausible but unproven at scale.
Related in Hormone Support
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