Antioxidant

PQQ (Pyrroloquinoline Quinone)

Also known as: BioPQQ, Pyrroloquinoline quinone

Evidence

Supports mitochondrial biogenesis - the creation of new mitochondria. Works synergistically with CoQ10.

Last reviewed June 2026 · Evidence graded from peer-reviewed research, not editorial opinion. Educational only — not medical advice.

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Primary uses

Mitochondrial biogenesis
Cognitive function
Energy
Longevity

How it works

Stimulates mitochondrial biogenesis
Nerve growth factor support
Potent antioxidant

Dosage

Typical range: 10-20 mg daily
Timing: Morning
With food: Optional
Duration: Safe long-term
Special populations: Aging, cognitive support

Forms

Capsules

Safety

Common side effects

Well tolerated

Contraindications

None

Products containing PQQ (Pyrroloquinoline Quinone)

Top-scoring supplements in our catalog that list PQQ (Pyrroloquinoline Quinone) on the label. Each product is graded on Formulate's ingredient-level rubric — dose accuracy, form, transparency, and third-party testing.

Transparent Labs

Longevity Healthy Aging Complex

Seed

• PM-02™ Sleep + Restore Supplement

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Evidence notes

Promotes new mitochondria

Grade B: Some human trials support key claims; further confirmation needed.

PQQ (Pyrroloquinoline Quinone) compared head-to-head

Mitochondrial Support
PQQ (Pyrroloquinoline Quinone) vs CoQ10 (Ubiquinone/Ubiquinol)

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Medical disclaimer. This page is educational and does not replace advice from a qualified healthcare provider. Individual needs and risks vary — consult a professional before starting, stopping, or combining supplements, especially if you are pregnant or nursing, taking medication, or managing a health condition.