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Nootropic

Phosphatidylcholine

Also known as: PC, Lecithin (contains PC)

B
Evidence

Major membrane phospholipid and choline source. Supports brain cell structure and liver health.

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Daily target & upper limit

550 mg / day · UL 3500 mg

Phosphatidylcholine has an established daily reference intake. See best forms, label synonyms, upper-limit warnings, and top-scoring supplements:

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Primary uses

  • Cell membranes
  • Choline supply
  • Liver health
  • Brain health

How it works

  • Cell membrane component
  • Choline source
  • Liver fat metabolism

Dosage

Typical range
500-2000 mg daily
Timing
With meals
With food
Yes
Duration
Safe long-term
Special populations
Liver health, choline needs

Forms

  • Softgels
  • Lecithin granules

Safety

Common side effects

  • GI upset
  • Fishy odor

Contraindications

  • None

Products containing Phosphatidylcholine

Top-scoring supplements in our catalog that list Phosphatidylcholine on the label. Each product is graded on Formulate's ingredient-level rubric — dose accuracy, form, transparency, and third-party testing.

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Evidence notes

Membrane and liver support

Grade B: Some human trials support key claims; further confirmation needed.

Cited research for Phosphatidylcholine

Clinical studies referenced across Formulate guides that mention phosphatidylcholine. Each links to the full study page with PubMed source + the guides that cite it.

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Medical disclaimer. This page is educational and does not replace advice from a qualified healthcare provider.