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Nootropic

DMAE

Also known as: DMAE (Dimethylaminoethanol), Deanol, Dimethylaminoethanol

B
Evidence

Choline precursor with membrane-stabilizing effects. Moderate nootropic effects.

Last reviewed June 2026 · Evidence graded from peer-reviewed research, not editorial opinion. Educational only — not medical advice.

Add NOW Foods True Focus to your stack — free
The highest-scored DMAE product in our catalog (80/100). Track dose and overlaps in the app.
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Every DMAE product we have scored

Scored on dose accuracy, form, label transparency and third-party testing. Per-serving cost is list price divided by servings per container. No brand pays to be listed or ranked.

Common questions

How much DMAE should I take?

The typical range is 100-300 mg daily. Safe long-term

When should I take DMAE?

Morning. Optional.

Which form of DMAE is best?

Capsules — Oral. Other forms in the catalog: Topical.

Is DMAE safe?

Commonly reported: Headache, Muscle tension, Insomnia. Serious warnings: May worsen depression. Safe

Which DMAE supplement scores highest?

NOW Foods True Focus, at 80/100. Scored on dose accuracy, form, label transparency and third-party testing — no brand pays to be listed or ranked.

Primary uses

  • Focus
  • Skin health
  • Choline support
  • Membrane health

How it works

  • Acetylcholine precursor (inefficient)
  • Cell membrane stabilizer
  • Topical skin benefits

Dosage

Typical range
100-300 mg daily
Timing
Morning
With food
Optional
Duration
Safe long-term
Special populations
Mild cognitive support

Forms

  • Capsules
  • Topical

Safety

Common side effects

  • Headache
  • Muscle tension
  • Insomnia

Contraindications

  • Bipolar
  • Depression
  • Epilepsy

Products containing DMAE

Top-scoring supplements in our catalog that list DMAE on the label. Each product is graded on Formulate's ingredient-level rubric — dose accuracy, form, transparency, and third-party testing.

Bluebonnet Nutrition
DMAE 100 mg
78
Bluebonnet Nutrition
POWER THOUGHT
74
See all products →

Evidence notes

Choline precursor with skin benefits

Grade B: Some human trials support key claims; further confirmation needed.

Related in Nootropic

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Medical disclaimer. This page is educational and does not replace advice from a qualified healthcare provider. Individual needs and risks vary — consult a professional before starting, stopping, or combining supplements, especially if you are pregnant or nursing, taking medication, or managing a health condition.