Nootropic

DMAE

Also known as: DMAE (Dimethylaminoethanol), Deanol, Dimethylaminoethanol

Evidence

Choline precursor with membrane-stabilizing effects. Moderate nootropic effects.

Last reviewed June 2026 · Evidence graded from peer-reviewed research, not editorial opinion. Educational only — not medical advice.

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Primary uses

Focus
Skin health
Choline support
Membrane health

How it works

Acetylcholine precursor (inefficient)
Cell membrane stabilizer
Topical skin benefits

Dosage

Typical range: 100-300 mg daily
Timing: Morning
With food: Optional
Duration: Safe long-term
Special populations: Mild cognitive support

Forms

Capsules
Topical

Safety

Common side effects

Headache
Muscle tension
Insomnia

Contraindications

Bipolar
Depression
Epilepsy

Evidence notes

Choline precursor with skin benefits

Grade B: Some human trials support key claims; further confirmation needed.

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Medical disclaimer. This page is educational and does not replace advice from a qualified healthcare provider. Individual needs and risks vary — consult a professional before starting, stopping, or combining supplements, especially if you are pregnant or nursing, taking medication, or managing a health condition.