Nootropic

Coluracetam

Also known as: MKC-231, BCI-540

Evidence

Racetam enhancing high-affinity choline uptake. Unique mechanism with vision and mood effects.

Last reviewed June 2026 · Evidence graded from peer-reviewed research, not editorial opinion. Educational only — not medical advice.

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Primary uses

Choline uptake
Vision enhancement
Mood
Memory

How it works

High-affinity choline uptake enhancement
May enhance color vision
Mood effects reported

Dosage

Typical range: 5-35 mg daily
Timing: Morning
With food: With fat
Duration: Effects develop over time
Special populations: Vision enhancement, mood

Forms

Powder
Capsules

Safety

Common side effects

Headache
Fatigue

Contraindications

Unknown

Evidence notes

Unique choline uptake mechanism

Grade C: Mostly observational or small trials; mechanism is plausible but unproven at scale.

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Medical disclaimer. This page is educational and does not replace advice from a qualified healthcare provider. Individual needs and risks vary — consult a professional before starting, stopping, or combining supplements, especially if you are pregnant or nursing, taking medication, or managing a health condition.