Herbal Extract
Mitidol® (Ginger & Acmella Phytosome®)
Also known as: Zingiber officinale CO2 extract, Acmella oleracea extract, Ginger acmella phytosome, Spilanthol ginger complex
Mitidol® combines standardized ginger rhizome extract (2.4% gingerols and shogaols) with Acmella oleracea (0.3% spilanthol) in a phytosome delivery system designed to enhance bioavailability. The combination targets inflammatory response and oral sensory stimulation, though evidence is primarily derived from individual component research rather than the proprietary blend itself.
Primary uses
- Anti-inflammatory support
- Digestive comfort
- Oral sensory stimulation
- General wellness
How it works
- Gingerols and shogaols inhibit prostaglandin and leukotriene synthesis
- Spilanthol provides localized oral stimulation and potential immune modulation
- Phytosome delivery enhances absorption and cellular uptake
Dosage
- Typical range
- As directed by manufacturer; typically 1-2 capsules daily
- Timing
- With meals for optimal absorption and reduced gastrointestinal upset
- With food
- Recommended with food to enhance phytosome absorption
- Duration
- Safe for long-term use; effects typically emerge after 2-4 weeks of consistent use
- Special populations
- Pregnant/nursing women should consult healthcare provider; may interact with blood thinners or medications metabolized via CYP3A4
Forms
- Capsule· 70/100
Safety
Common side effects
- Mild gastrointestinal discomfort (ginger-related)
- Oral numbness or tingling (acmella-related)
Contraindications
- Bleeding disorders or anticoagulant therapy (ginger may potentiate effects)
- Gallstones or bile duct obstruction (ginger contraindication)
- Pregnancy and lactation (insufficient safety data for proprietary blend)
- Allergy to Zingiberaceae or Asteraceae families
Evidence notes
Ginger alone has B-grade evidence for anti-inflammatory effects, but the proprietary Mitidol® blend combining ginger phytosome with Acmella lacks dedicated human clinical trials. Acmella oleracea has limited human data. The specific combination and phytosome formulation represent a novel product with preliminary evidence at best.
Grade C: Mostly observational or small trials; mechanism is plausible but unproven at scale.
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