Mineral

Manganese (as Fermented Manganese Bisglycinate)

Also known as: manganese bisglycinate, fermented manganese, chelated manganese

Evidence

Manganese is an essential trace mineral involved in bone development, metabolism, and antioxidant defenses. The bisglycinate form provides optimal absorption with minimal GI side effects.

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Daily target & upper limit

2.3 mg / day · UL 11 mg

Manganese (as Fermented Manganese Bisglycinate) has an established daily reference intake. See best forms, label synonyms, upper-limit warnings, and top-scoring supplements:

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Primary uses

Bone mineralization and skeletal development
Antioxidant defense (manganese SOD)
Carbohydrate and amino acid metabolism
Fetal growth and development

How it works

Cofactor for manganese superoxide dismutase (MnSOD)
Required for bone matrix synthesis
Involved in proteoglycan synthesis
Supports aromatase and other metalloenzymes

Dosage

Typical range: 2 mg daily (RDA for pregnant women)
Timing: with meals preferred
With food: take with food to enhance absorption
Duration: throughout pregnancy and lactation
Special populations: Pregnant women 2 mg/day; lactating women 2.6 mg/day; do not exceed 11 mg/day

Forms

manganese bisglycinate· 70/100
manganese citrate· 70/100

Safety

Products containing Manganese (as Fermented Manganese Bisglycinate)

Top-scoring supplements in our catalog that list Manganese (as Fermented Manganese Bisglycinate) on the label. Each product is graded on Formulate's ingredient-level rubric — dose accuracy, form, transparency, and third-party testing.

Thorne

MediClear-SGS™ - Vanilla

Thorne

Basic Nutrients 2/Day

Evidence notes

Established role in fetal skeletal development; less extensive RCT data compared to iron or zinc; deficiency is rare in prenatal populations; safety and efficacy at recommended doses well-documented.

Grade C: Mostly observational or small trials; mechanism is plausible but unproven at scale.

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Medical disclaimer. This page is educational and does not replace advice from a qualified healthcare provider.