Mineral
Manganese (as Fermented Manganese Bisglycinate)
Also known as: manganese bisglycinate, fermented manganese, chelated manganese
Manganese is an essential trace mineral involved in bone development, metabolism, and antioxidant defenses. The bisglycinate form provides optimal absorption with minimal GI side effects.
Last reviewed June 2026 · Evidence graded from peer-reviewed research, not editorial opinion. Educational only — not medical advice.
Every Manganese (as Fermented Manganese Bisglycinate) product we have scored
| # | Product | Score | Per serving |
|---|---|---|---|
| 1 | Thorne Advanced Nutrients | 88 A | $2.40 |
| 2 | Thorne Basic Nutrients 2/Day | 88 A | $0.60 |
| 3 | Thorne Basic Prenatal | 88 A | $1.23 |
| 4 | Thorne Men's Multi 50+ | 88 A | $1.87 |
| 5 | Pure Encapsulations Glucosamine Chondroitin with Manganese | 87 A | $0.54 |
| 6 | Garden of Life Vitamin Code 50 & Wiser Women | 87 A | $1.01 |
| 7 | Thorne MediClear-SGS™ - Vanilla | 86 A- | $2.10 |
| 8 | Transparent Labs Multivitamin | 86 A- | $1.33 |
| 9 | Seed AM-02™ Energy + Focus Supplement | 86 A- | $1.17 |
| 10 | Garden of Life Organics Women's Multi 40+ | 86 A- | $1.07 |
| 11 | Garden of Life Vitamin Code Raw One for Men | 86 A- | $0.41 |
| 12 | Garden of Life Organics Men's Multi | 86 A- | $1.16 |
Scored on dose accuracy, form, label transparency and third-party testing. Per-serving cost is list price divided by servings per container. No brand pays to be listed or ranked.
Common questions
How much Manganese (as Fermented Manganese Bisglycinate) should I take?
The typical range is 2 mg daily (RDA for pregnant women). throughout pregnancy and lactation
When should I take Manganese (as Fermented Manganese Bisglycinate)?
with meals preferred. take with food to enhance absorption.
Which form of Manganese (as Fermented Manganese Bisglycinate) is best?
manganese bisglycinate. Other forms in the catalog: manganese citrate.
Which Manganese (as Fermented Manganese Bisglycinate) supplement scores highest?
Thorne Advanced Nutrients, at 88/100. Scored on dose accuracy, form, label transparency and third-party testing — no brand pays to be listed or ranked.
Daily target & upper limit
2.3 mg / day · UL 11 mgManganese (as Fermented Manganese Bisglycinate) has an established daily reference intake. See best forms, label synonyms, upper-limit warnings, and top-scoring supplements:
Manganese (as Fermented Manganese Bisglycinate) dosage reference →Primary uses
- Bone mineralization and skeletal development
- Antioxidant defense (manganese SOD)
- Carbohydrate and amino acid metabolism
- Fetal growth and development
How it works
- Cofactor for manganese superoxide dismutase (MnSOD)
- Required for bone matrix synthesis
- Involved in proteoglycan synthesis
- Supports aromatase and other metalloenzymes
Dosage
- Typical range
- 2 mg daily (RDA for pregnant women)
- Timing
- with meals preferred
- With food
- take with food to enhance absorption
- Duration
- throughout pregnancy and lactation
- Special populations
- Pregnant women 2 mg/day; lactating women 2.6 mg/day; do not exceed 11 mg/day
Forms
- manganese bisglycinate· 70/100
- manganese citrate· 70/100
Safety
Products containing Manganese (as Fermented Manganese Bisglycinate)
Top-scoring supplements in our catalog that list Manganese (as Fermented Manganese Bisglycinate) on the label. Each product is graded on Formulate's ingredient-level rubric — dose accuracy, form, transparency, and third-party testing.
Evidence notes
Established role in fetal skeletal development; less extensive RCT data compared to iron or zinc; deficiency is rare in prenatal populations; safety and efficacy at recommended doses well-documented.
Grade C: Mostly observational or small trials; mechanism is plausible but unproven at scale.
Related in Mineral
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Medical disclaimer. This page is educational and does not replace advice from a qualified healthcare provider. Individual needs and risks vary — consult a professional before starting, stopping, or combining supplements, especially if you are pregnant or nursing, taking medication, or managing a health condition.