Mineral
Manganese (as Fermented Manganese Bisglycinate)
Also known as: manganese bisglycinate, fermented manganese, chelated manganese
Manganese is an essential trace mineral involved in bone development, metabolism, and antioxidant defenses. The bisglycinate form provides optimal absorption with minimal GI side effects.
Last reviewed June 2026 · Evidence graded from peer-reviewed research, not editorial opinion. Educational only — not medical advice.
Daily target & upper limit
2.3 mg / day · UL 11 mgManganese (as Fermented Manganese Bisglycinate) has an established daily reference intake. See best forms, label synonyms, upper-limit warnings, and top-scoring supplements:
Manganese (as Fermented Manganese Bisglycinate) dosage reference →Primary uses
- Bone mineralization and skeletal development
- Antioxidant defense (manganese SOD)
- Carbohydrate and amino acid metabolism
- Fetal growth and development
How it works
- Cofactor for manganese superoxide dismutase (MnSOD)
- Required for bone matrix synthesis
- Involved in proteoglycan synthesis
- Supports aromatase and other metalloenzymes
Dosage
- Typical range
- 2 mg daily (RDA for pregnant women)
- Timing
- with meals preferred
- With food
- take with food to enhance absorption
- Duration
- throughout pregnancy and lactation
- Special populations
- Pregnant women 2 mg/day; lactating women 2.6 mg/day; do not exceed 11 mg/day
Forms
- manganese bisglycinate· 70/100
- manganese citrate· 70/100
Safety
Products containing Manganese (as Fermented Manganese Bisglycinate)
Top-scoring supplements in our catalog that list Manganese (as Fermented Manganese Bisglycinate) on the label. Each product is graded on Formulate's ingredient-level rubric — dose accuracy, form, transparency, and third-party testing.
Evidence notes
Established role in fetal skeletal development; less extensive RCT data compared to iron or zinc; deficiency is rare in prenatal populations; safety and efficacy at recommended doses well-documented.
Grade C: Mostly observational or small trials; mechanism is plausible but unproven at scale.
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Medical disclaimer. This page is educational and does not replace advice from a qualified healthcare provider. Individual needs and risks vary — consult a professional before starting, stopping, or combining supplements, especially if you are pregnant or nursing, taking medication, or managing a health condition.