Mineral
Calcium Gluconate
Also known as: Calcium gluconate, Gluconic acid calcium salt, Calcium salt of gluconic acid
Calcium gluconate is an organic calcium salt with high solubility and bioavailability, used to support bone health, muscle function, and cellular signaling. It is well-established that adequate calcium intake is essential for skeletal integrity and cardiovascular function.
Primary uses
- Bone health and mineralization
- Muscle contraction and function
- Nerve transmission
- Cardiovascular health
- Calcium supplementation
How it works
- Provides bioavailable calcium for bone matrix formation and maintenance
- Supports excitation-contraction coupling in muscle tissue
- Enables calcium-dependent cell signaling pathways
- Regulates neuromuscular transmission
Dosage
- Typical range
- 500–1200 mg elemental calcium daily (divided doses preferred)
- Timing
- With meals to enhance absorption; divide into 2–3 doses for optimal uptake
- With food
- Recommended—food enhances calcium absorption
- Duration
- Long-term daily use appropriate for bone health maintenance; consistent intake recommended
- Special populations
- Postmenopausal women, older adults, and those with low dietary calcium intake benefit most; requirements increase with age
Forms
- Powder· 70/100
- Capsule· 70/100
- Tablet· 70/100
Safety
Common side effects
- Constipation
- Bloating
- Gas
- Mild gastrointestinal discomfort
Contraindications
- Hypercalcemia or elevated serum calcium
- Kidney disease (consult physician)
- Hyperparathyroidism
- Sarcoidosis or granulomatous disease
Evidence notes
Calcium's role in bone health and general physiology is extensively documented through large RCTs and meta-analyses. Gluconate is a well-absorbed organic form with established bioavailability compared to inorganic salts.
Grade A: Multiple well-designed human trials support the main claims.
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