Mineral
GTF Chromium (as Fermented Chromium Glycinate, Nicotinate, Glutamate)
Also known as: GTF chromium, glucose tolerance factor chromium, chromium polynicotinate, fermented chromium
GTF (Glucose Tolerance Factor) chromium is a bioactive form of chromium that supports glucose metabolism and insulin sensitivity. The fermented delivery system with glycinate and nicotinate ligands is designed to enhance absorption and biological activity.
Last reviewed June 2026 · Evidence graded from peer-reviewed research, not editorial opinion. Educational only — not medical advice.
Every GTF Chromium (as Fermented Chromium Glycinate, Nicotinate, Glutamate) product we have scored
| # | Product | Score | Per serving |
|---|---|---|---|
| 1 | Performance Lab NutriGenesis Multi for Men | 86 A- | $1.63 |
| 2 | Bluebonnet Nutrition GTF CHROMIUM 200 mcg | 81 A- | $0.17 |
| 3 | MegaFood Baby & Me 2 Prenatal Multi Minis | 77 B+ | $1.03 |
| 4 | MegaFood Men's 40+ Advanced Multivitamin | 76 B+ | $0.93 |
| 5 | MegaFood Women's 40+ Advanced Multivitamin | 75 B+ | $0.93 |
| 6 | MegaFood Women's Advanced Multivitamin | 75 B+ | $1.03 |
| 7 | MegaFood Men's Advanced Multivitamin | 75 B+ | $0.93 |
| 8 | MegaFood Baby & Me 2 Prenatal Multi | 74 B+ | $0.93 |
| 9 | MegaFood Women’s One Daily Multivitamin | 73 B+ | $0.52 |
| 10 | MegaFood Men's 55+ Advanced Multivitamin | 73 B+ | $0.85 |
| 11 | MegaFood Men's 40+ One Daily Multivitamin | 73 B+ | $0.52 |
| 12 | MegaFood Women's 40+ One Daily Multivitamin | 72 B | $0.63 |
Scored on dose accuracy, form, label transparency and third-party testing. Per-serving cost is list price divided by servings per container. No brand pays to be listed or ranked.
Common questions
How much GTF Chromium (as Fermented Chromium Glycinate, Nicotinate, Glutamate) should I take?
The typical range is 200 mcg daily (Adequate Intake for adults; no specific RDA for pregnancy). throughout pregnancy if indicated for glucose support
When should I take GTF Chromium (as Fermented Chromium Glycinate, Nicotinate, Glutamate)?
with meals preferred. take with food to enhance absorption.
Which form of GTF Chromium (as Fermented Chromium Glycinate, Nicotinate, Glutamate) is best?
GTF chromium. Other forms in the catalog: chromium polynicotinate, chromium picolinate.
Which GTF Chromium (as Fermented Chromium Glycinate, Nicotinate, Glutamate) supplement scores highest?
Performance Lab NutriGenesis Multi for Men, at 86/100. Scored on dose accuracy, form, label transparency and third-party testing — no brand pays to be listed or ranked.
Daily target & upper limit
35 mcg / dayGTF Chromium (as Fermented Chromium Glycinate, Nicotinate, Glutamate) has an established daily reference intake. See best forms, label synonyms, upper-limit warnings, and top-scoring supplements:
GTF Chromium (as Fermented Chromium Glycinate, Nicotinate, Glutamate) dosage reference →Primary uses
- Glucose metabolism support
- Carbohydrate utilization
- Insulin sensitivity
- Blood sugar stability
How it works
- Enhances insulin receptor signaling
- Potentiates insulin action on muscle and adipose tissue
- Supports glucose transporter activity
- Cofactor for glucose tolerance factor complex
Dosage
- Typical range
- 200 mcg daily (Adequate Intake for adults; no specific RDA for pregnancy)
- Timing
- with meals preferred
- With food
- take with food to enhance absorption
- Duration
- throughout pregnancy if indicated for glucose support
- Special populations
- Pregnant women 200 mcg/day (based on AI); do not exceed 200 mcg/day in pregnancy due to limited data
Forms
- GTF chromium· 70/100
- chromium polynicotinate· 70/100
- chromium picolinate· 70/100
Safety
Contraindications
- Diabetes (requires medical supervision if adding beyond prenatal multivitamin)
Products containing GTF Chromium (as Fermented Chromium Glycinate, Nicotinate, Glutamate)
Top-scoring supplements in our catalog that list GTF Chromium (as Fermented Chromium Glycinate, Nicotinate, Glutamate) on the label. Each product is graded on Formulate's ingredient-level rubric — dose accuracy, form, transparency, and third-party testing.
Evidence notes
Moderate evidence for chromium in glucose metabolism; GTF form is theoretically more bioavailable than inorganic chromium salts, but direct RCT evidence is limited; fermented delivery method is proprietary with preliminary data; safe at typical prenatal doses.
Grade C: Mostly observational or small trials; mechanism is plausible but unproven at scale.
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Medical disclaimer. This page is educational and does not replace advice from a qualified healthcare provider. Individual needs and risks vary — consult a professional before starting, stopping, or combining supplements, especially if you are pregnant or nursing, taking medication, or managing a health condition.