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Mineral

GTF Chromium (as Fermented Chromium Glycinate, Nicotinate, Glutamate)

Also known as: GTF chromium, glucose tolerance factor chromium, chromium polynicotinate, fermented chromium

C
Evidence

GTF (Glucose Tolerance Factor) chromium is a bioactive form of chromium that supports glucose metabolism and insulin sensitivity. The fermented delivery system with glycinate and nicotinate ligands is designed to enhance absorption and biological activity.

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Daily target & upper limit

35 mcg / day

GTF Chromium (as Fermented Chromium Glycinate, Nicotinate, Glutamate) has an established daily reference intake. See best forms, label synonyms, upper-limit warnings, and top-scoring supplements:

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Primary uses

  • Glucose metabolism support
  • Carbohydrate utilization
  • Insulin sensitivity
  • Blood sugar stability

How it works

  • Enhances insulin receptor signaling
  • Potentiates insulin action on muscle and adipose tissue
  • Supports glucose transporter activity
  • Cofactor for glucose tolerance factor complex

Dosage

Typical range
200 mcg daily (Adequate Intake for adults; no specific RDA for pregnancy)
Timing
with meals preferred
With food
take with food to enhance absorption
Duration
throughout pregnancy if indicated for glucose support
Special populations
Pregnant women 200 mcg/day (based on AI); do not exceed 200 mcg/day in pregnancy due to limited data

Forms

  • GTF chromium· 70/100
  • chromium polynicotinate· 70/100
  • chromium picolinate· 70/100

Safety

Contraindications

  • Diabetes (requires medical supervision if adding beyond prenatal multivitamin)

Evidence notes

Moderate evidence for chromium in glucose metabolism; GTF form is theoretically more bioavailable than inorganic chromium salts, but direct RCT evidence is limited; fermented delivery method is proprietary with preliminary data; safe at typical prenatal doses.

Grade C: Mostly observational or small trials; mechanism is plausible but unproven at scale.

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Medical disclaimer. This page is educational and does not replace advice from a qualified healthcare provider.