Joint Health
Glucosamine Sulfate
Also known as: Glucosamine
The most studied form for joint health. Building block for cartilage. Works over weeks-months.
Primary uses
- Joint health
- Cartilage support
- Osteoarthritis
How it works
- Provides building blocks for cartilage
- May slow cartilage degradation
- Anti-inflammatory effects
Dosage
- Typical range
- 1500mg daily (often split)
- Timing
- With or without food
- With food
- Optional (may reduce GI)
- Duration
- 3-6 months for effect
- Special populations
- Osteoarthritis, joint wear
Forms
- Sulfate crystalline
- HCl
Safety
Common side effects
- Mild GI upset
- Headache
Contraindications
- Shellfish allergy (if derived from shellfish)
Products containing Glucosamine Sulfate
Top-scoring supplements in our catalog that list Glucosamine Sulfate on the label. Each product is graded on Formulate's ingredient-level rubric — dose accuracy, form, transparency, and third-party testing.
Evidence notes
Well-studied for OA, sulfate form preferred
Grade A: Multiple well-designed human trials support the main claims.
Cited research for Glucosamine Sulfate
Clinical studies referenced across Formulate guides that mention glucosamine sulfate. Each links to the full study page with PubMed source + the guides that cite it.
- Clegg DO, Reda DJ, Harris CL, et al. (2006)New England Journal of Medicine
Glucosamine, chondroitin sulfate, and the two in combination for painful knee osteoarthritis (GAIT trial)
- Reginster JY, Deroisy R, Rovati LC, et al. (2001)Lancet
Long-term effects of glucosamine sulphate on osteoarthritis progression: a randomised, placebo-controlled clinical trial
Glucosamine Sulfate compared head-to-head
Related in Joint Health
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