Joint Health
Devil's Claw
Also known as: Harpagophytum procumbens
African herb traditionally used for joint pain and inflammation. Alternative to NSAIDs.
Last reviewed June 2026 · Evidence graded from peer-reviewed research, not editorial opinion. Educational only — not medical advice.
Every Devil's Claw product we have scored
| # | Product | Score | Per serving |
|---|---|---|---|
| 1 | Pure Encapsulations Phyto UltraComfort | 85 A- | $1.05 |
| 2 | BulkSupplements Devil's Claw Extract Capsules | 85 A- | $0.20 |
| 3 | Pure Encapsulations Uric Acid Formula | 79 B+ | $0.43 |
| 4 | Natural Factors Joint Curcumizer | 79 B+ | $1.17 |
| 5 | Pure Encapsulations Ligament Restore | 76 B+ | $1.05 |
| 6 | Pure Encapsulations Disc-Flex | 75 B+ | $1.41 |
Scored on dose accuracy, form, label transparency and third-party testing. Per-serving cost is list price divided by servings per container. No brand pays to be listed or ranked.
Common questions
How much Devil's Claw should I take?
The typical range is 600-1200mg standardized extract. 4-8 weeks for effect
When should I take Devil's Claw?
With meals. Yes.
Which form of Devil's Claw is best?
Standardized extract — Harpagoside content.
Is Devil's Claw safe?
Commonly reported: GI upset, Diarrhea. Serious warnings: May affect blood pressure, May increase stomach acid. Safe at moderate doses
Which Devil's Claw supplement scores highest?
Pure Encapsulations Phyto UltraComfort, at 85/100. Scored on dose accuracy, form, label transparency and third-party testing — no brand pays to be listed or ranked.
Primary uses
- Joint pain
- Back pain
- Inflammation
- Arthritis
How it works
- Anti-inflammatory
- May inhibit pain mediators
- Traditional use
Dosage
- Typical range
- 600-1200mg standardized extract
- Timing
- With meals
- With food
- Yes
- Duration
- 4-8 weeks for effect
- Special populations
- Joint pain, back pain, OA
Forms
- Standardized extract
Safety
Common side effects
- GI upset
- Diarrhea
Contraindications
- Peptic ulcer
- Gallstones
- Pregnancy
Products containing Devil's Claw
Top-scoring supplements in our catalog that list Devil's Claw on the label. Each product is graded on Formulate's ingredient-level rubric — dose accuracy, form, transparency, and third-party testing.
Evidence notes
Traditional joint remedy
Grade B: Some human trials support key claims; further confirmation needed.
Related in Joint Health
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Medical disclaimer. This page is educational and does not replace advice from a qualified healthcare provider. Individual needs and risks vary — consult a professional before starting, stopping, or combining supplements, especially if you are pregnant or nursing, taking medication, or managing a health condition.