Joint Health
Avocado-Soy Unsaponifiables (ASU)
Also known as: ASU, Piascledine
Lipid extract that may protect cartilage and reduce need for NSAIDs in osteoarthritis.
Last reviewed June 2026 · Evidence graded from peer-reviewed research, not editorial opinion. Educational only — not medical advice.
Primary uses
- Cartilage protection
- Osteoarthritis
- Joint health
How it works
- May inhibit cartilage breakdown
- Anti-inflammatory
- Supports cartilage matrix
Dosage
- Typical range
- 300mg daily
- Timing
- With food
- With food
- Yes
- Duration
- 3+ months for effects
- Special populations
- Osteoarthritis, cartilage protection
Forms
- Capsules
Safety
Common side effects
- GI upset
Contraindications
- Soy allergy
Evidence notes
European OA treatment
Grade B: Some human trials support key claims; further confirmation needed.
Related in Joint Health
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Medical disclaimer. This page is educational and does not replace advice from a qualified healthcare provider. Individual needs and risks vary — consult a professional before starting, stopping, or combining supplements, especially if you are pregnant or nursing, taking medication, or managing a health condition.