Herbal Extract
Epimedium brevicornum Extract (Leaf) - 10% Icariin
Also known as: Horny Goat Weed, Epimedium, Yin Yang Huo, Icariin
A traditional Chinese herb extract standardized to 10% icariin, a prenylated flavonol compound used for sexual function and vascular health. Icariin acts as a phosphodiesterase-5 (PDE-5) inhibitor.
Primary uses
- Sexual function and erectile quality
- Vascular endothelial function
- Bone health
- Energy and stamina
How it works
- PDE-5 inhibition (similar to pharmaceutical ED drugs)
- Nitric oxide pathway enhancement
- Improved blood flow
- Anti-inflammatory effects
Dosage
- Typical range
- 500-1000 mg daily of 10% icariin extract (providing ~50-100 mg icariin)
- Timing
- Typically taken 30-60 minutes before sexual activity, or daily for chronic use
- With food
- May take with or without food; fatty meals may enhance absorption
- Duration
- Acute effects noted within 1-2 hours; chronic benefits develop over 2-4 weeks of daily use
- Special populations
- Caution in individuals taking nitrates or other ED medications; monitor blood pressure
Forms
- Extract· 70/100
- Capsule· 70/100
Safety
Common side effects
- Flushing
- Headache
- Mild digestive upset
- Dizziness
Contraindications
- Concurrent use with nitrates or phosphodiesterase inhibitors (sildenafil, etc.)
- Uncontrolled hypertension
- Recent cardiac events
- Severe liver or kidney disease
Evidence notes
In vivo and clinical studies support PDE-5 inhibition and erectile function improvement; human RCT data is moderate but emerging. 10% icariin is a meaningful standardization level.
Grade B: Some human trials support key claims; further confirmation needed.
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