High Potency Optimized Folate L-Methylfolate
Scored by the Formulate Research Team · Last reviewed July 2026
Score Breakdown
Three factors carry this score; three more are checked separately and can only take points away. Hover or tap to see what drove each one.
Ingredients per Serving
Certifications & Testing
Other Ingredients
Microcrystalline Cellulose, Dicalcium Phosphate, Stearic Acid, Croscarmellose Sodium, Silica, Vegetable Stearate
Recommended Use
Read the entire label and follow the directions carefully prior to use. Directions: Take one (1) tablet daily with food, or as recommended by a healthcare practitioner.
Warnings
Caution: Do not use this product if treated with methotrexate, fluorouracil, phenytoin, phenobarbital, primidone, or levodopa prior to consultation with your personal physician. Warnings: Keep out of reach of children. Do not exceed recommended dose. Do not purchase if outer seal is broken or damaged. When using nutritional supplements, please consult with your physician if you are undergoing trea
Frequently Asked Questions
What is Life Extension High Potency Optimized Folate L-Methylfolate's Formulate score?
Life Extension High Potency Optimized Folate L-Methylfolate scores 85 out of 100 (grade A-) on Formulate's ingredient-level rubric: clinical evidence, dose accuracy and bioavailability carry the score, while manufacturing, transparency and safety are checked separately and can only deduct.
Is Life Extension High Potency Optimized Folate L-Methylfolate worth it?
Life Extension High Potency Optimized Folate L-Methylfolate scores 85/100 (grade A-). That puts it in Formulate's top tier: its ingredient doses, forms, and label transparency hold up against the clinical evidence, and it carries credible third-party testing. Formulate grades every product with the same automated rubric, so the score reflects the formula — not marketing or sponsorships.
What's in Life Extension High Potency Optimized Folate L-Methylfolate?
Each serving contains Folate (8500 mcg DFE). Serving size: 1 Vegetarian Tablet(s). 30 servings per container.
How do I take high potency optimized folate l-methylfolate?
Read the entire label and follow the directions carefully prior to use. Directions: Take one (1) tablet daily with food, or as recommended by a healthcare practitioner.
Who makes High Potency Optimized Folate L-Methylfolate?
High Potency Optimized Folate L-Methylfolate is made by Life Extension. See Formulate's full grade and product lineup for Life Extension on its brand page.
Is Life Extension High Potency Optimized Folate L-Methylfolate third-party tested?
Life Extension lists the following certifications and testing for this product: Gluten free Non GMO LE Certified, Vegetarian, Gluten-Free.
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Disclosure. Formulate may earn a commission from purchases made through links on this page. Commissions never influence scores — every product is graded by the same automated rubric. This page is for educational purposes only and does not replace advice from a qualified healthcare provider.