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collagen and vitamin c

Vitamin C is required for collagen synthesis

What's happening

Vitamin C is a cofactor for prolyl and lysyl hydroxylase, the enzymes that cross-link collagen fibers. Without adequate vitamin C the body cannot effectively incorporate collagen amino acids into new tissue.

Recommendation

Take 50-500mg vitamin C with collagen peptides (10-20g) for best use.

Timing

Take together

Sources

  • Amino Acids 2006
  • PMID: 16622713

Frequently Asked Questions

Can I take collagen and vitamin c together?

Vitamin C is required for collagen synthesis. Take 50-500mg vitamin C with collagen peptides (10-20g) for best use.

How should I time collagen and vitamin c?

Take together

Is this interaction dangerous?

This interaction is rated “Synergy” by Formulate. Vitamin C is a cofactor for prolyl and lysyl hydroxylase, the enzymes that cross-link collagen fibers. Without adequate vitamin C the body cannot effectively incorporate collagen amino acids into new tissue.

Want to check your whole stack?

The free checker lets you add any combination of supplements and medications at once. Formulate's desktop app goes further — every stack change surfaces interaction alerts automatically.

Medical disclaimer. This page is for educational purposes only and does not replace advice from a qualified healthcare provider.