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aspirin and ginkgo biloba

Ginkgo + Aspirin: High bleeding risk

What's happening

Both ginkgo and aspirin inhibit platelet aggregation through different mechanisms. Ginkgo inhibits platelet-activating factor (PAF), while aspirin inhibits COX-1. Combined effect significantly increases bleeding risk, including intracranial bleeding.

Recommendation

Avoid ginkgo if taking aspirin regularly. If combining, inform all doctors.

Timing

Stop ginkgo 2 weeks before any surgery

Sources

  • — Neurology
  • — PMID: 8602755
  • — Lancet 1999;352:36

Frequently Asked Questions

Can I take aspirin and ginkgo biloba together?

Ginkgo + Aspirin: High bleeding risk. Avoid ginkgo if taking aspirin regularly. If combining, inform all doctors.

How should I time aspirin and ginkgo biloba?

Stop ginkgo 2 weeks before any surgery

Is this interaction dangerous?

This interaction is rated “Danger” by Formulate. Both ginkgo and aspirin inhibit platelet aggregation through different mechanisms. Ginkgo inhibits platelet-activating factor (PAF), while aspirin inhibits COX-1. Combined effect significantly increases bleeding risk, including intracranial bleeding.

Want to check your whole stack?

The free checker lets you add any combination of supplements and medications at once. Formulate's desktop app goes further — every stack change surfaces interaction alerts automatically.

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Medical disclaimer. This page is for educational purposes only and does not replace advice from a qualified healthcare provider.